In vivo and in vitro degradation of peptide YY3-36 to inactive peptide YY3-34 in humans

Peptide YY (PYY) is a 36-amino-acid peptide released from enteroendocrine cells upon food intake. The NH2 terminally truncated metabolite, PYY3-36, exerts anorexic effects and has received considerable attention as a possible antiobesity drug target. The kinetics and degradation products of PYY meta...

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Bibliographic Details
Published in:	American journal of physiology. Regulatory, integrative and comparative physiology Vol. 310; no. 9; pp. R866 - R874
Main Authors:	Toräng, Signe, Bojsen-Møller, Kirstine Nyvold, Svane, Maria Saur, Hartmann, Bolette, Rosenkilde, Mette Marie, Madsbad, Sten, Holst, Jens Juul
Format:	Journal Article
Language:	English
Published:	United States 01.05.2016
Subjects:	Animals Blood Glucose Blood Pressure Cercopithecus aethiops COS Cells Humans Male Peptide Fragments - chemistry Peptide Fragments - metabolism Peptide YY - chemistry Peptide YY - metabolism Proteolysis Single-Blind Method Young Adult kinetics degradation peptide YY
ISSN:	1522-1490
Online Access:	Get more information
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