Humanized mouse models of immunological diseases and precision medicine

With the increase in knowledge resulting from the sequencing of the human genome, the genetic basis for the underlying differences in individuals, their diseases, and how they respond to therapies is starting to be understood. This has formed the foundation for the era of precision medicine in many...

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Bibliographic Details
Published in:	Mammalian genome Vol. 30; no. 5-6; pp. 123 - 142
Main Authors:	Shultz, Leonard D., Keck, James, Burzenski, Lisa, Jangalwe, Sonal, Vaidya, Shantashri, Greiner, Dale L., Brehm, Michael A.
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.06.2019 Springer Nature B.V
Subjects:	Animal Genetics and Genomics Animal models Animals Biomedical and Life Sciences Cancer Cell Biology Cell Transplantation Disease Models, Animal genome Genomes human diseases Human Genetics Humans Immune response immune system Immune System - cytology Immune System - physiology Immune System Diseases - genetics Immune System Diseases - immunology Immune System Diseases - pathology Immunodeficiency immunologic diseases Immunological diseases Life Sciences Mice neoplasms patients Precision Medicine Rodents tissues Transplantation, Heterologous
ISSN:	0938-8990, 1432-1777, 1432-1777
Online Access:	Get full text
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