Global estimates and determinants of antituberculosis drug pharmacokinetics in children and adolescents: a systematic review and individual patient data meta-analysis

Suboptimal exposure to antituberculosis (anti-TB) drugs has been associated with unfavourable treatment outcomes. We aimed to investigate estimates and determinants of first-line anti-TB drug pharmacokinetics in children and adolescents at a global level. We systematically searched MEDLINE, Embase a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The European respiratory journal Jg. 61; H. 3
Hauptverfasser:	Gafar, Fajri, Wasmann, Roeland E, McIlleron, Helen M, Aarnoutse, Rob E, Schaaf, H Simon, Marais, Ben J, Agarwal, Dipti, Antwi, Sampson, Bang, Nguyen D, Bekker, Adrie, Bell, David J, Chabala, Chishala, Choo, Louise, Davies, Geraint R, Day, Jeremy N, Dayal, Rajeshwar, Denti, Paolo, Donald, Peter R, Engidawork, Ephrem, Garcia-Prats, Anthony J, Gibb, Diana, Graham, Stephen M, Hesseling, Anneke C, Heysell, Scott K, Idris, Misgana I, Kabra, Sushil K, Kinikar, Aarti, Kumar, Agibothu K Hemanth, Kwara, Awewura, Lodha, Rakesh, Magis-Escurra, Cecile, Martinez, Nilza, Mathew, Binu S, Mave, Vidya, Mduma, Estomih, Mlotha-Mitole, Rachel, Mpagama, Stellah G, Mukherjee, Aparna, Nataprawira, Heda M, Peloquin, Charles A, Pouplin, Thomas, Ramachandran, Geetha, Ranjalkar, Jaya, Roy, Vandana, Ruslami, Rovina, Shah, Ira, Singh, Yatish, Sturkenboom, Marieke G G, Svensson, Elin M, Swaminathan, Soumya, Thatte, Urmila, Thee, Stephanie, Thomas, Tania A, Tikiso, Tjokosela, Touw, Daan J, Turkova, Anna, Velpandian, Thirumurthy, Verhagen, Lilly M, Winckler, Jana L, Yang, Hongmei, Yunivita, Vycke, Taxis, Katja, Stevens, Jasper, Alffenaar, Jan-Willem C
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England 01.03.2023
Schlagworte:	Adolescent Antitubercular Agents - therapeutic use Child Child, Preschool Ethambutol - therapeutic use Humans Isoniazid - therapeutic use Pyrazinamide - therapeutic use Rifampin - therapeutic use
ISSN:	1399-3003, 1399-3003
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!