Design and Synthesis of 68Ga‐Labeled Peptide‐Based Heterodimers for Dual Targeting of NTS1 and GRPR

Tumor heterogeneity remains one of the main obstacles for cancer diagnosis and treatment. The simultaneous targeting of several cancer biomarkers is an appealing approach for improved diagnostic procedures. Neurotensin receptor 1 (NTS1) and Gastrin‐Releasing Peptide Receptor (GRPR) are both G‐protei...

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Bibliographic Details
Published in:	ChemMedChem Vol. 20; no. 9; pp. e202400843 - n/a
Main Authors:	Bodin, Sacha, Previti, Santo, Jestin, Emmanuelle, Rémond, Emmanuelle, Vimont, Delphine, Lamare, Frédéric, Ait‐Arsa, Imade, Hindié, Elif, Cavelier, Florine, Morgat, Clément
Format:	Journal Article
Language:	English
Published:	WEINHEIM Wiley 05.05.2025 Wiley Subscription Services, Inc John Wiley and Sons Inc
Subjects:	Affinity Biomarkers Bombesin Cancer Chemistry, Medicinal Efflux Gallium Gallium isotopes Gastrin GRPR Heterodimers Heterogeneity Hybrids Internalization Life Sciences & Biomedicine Neurotensin NTS1 Peptides PET imaging Pharmaceuticals Pharmacology & Pharmacy Pharmacophores Radiochemistry Radioisotopes Radiolabelling Receptors Science & Technology Synthesis NTS1 PSMA Bombesin ANTAGONIST PET imaging Heterodimers RECEPTOR Neurotensin GASTRIN-RELEASING-PEPTIDE GRPR PRIMARY PROSTATE-CANCER EXPRESSION
ISSN:	1860-7179, 1860-7187, 1860-7187
Online Access:	Get full text
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