Role of BH4 deficiency as a mediator of oxidative stress-related endothelial dysfunction in menopausal women

Endothelial function (brachial artery flow-mediated dilation [FMD]) is reduced in estrogen-deficient postmenopausal women, mediated, in part, by reduced nitric oxide (NO) bioavailability, secondary to tetrahydrobiopterin (BH4) deficiency and oxidative stress. FMD is increased, but not fully restored...

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Bibliographic Details

Published in:	American journal of physiology. Heart and circulatory physiology Vol. 323; no. 5; p. H975
Main Authors:	DuBose, Lyndsey E, Ozemek, Cemal, Wick, Tyler, Richardson, Vanessa, Hildreth, Kerry L, Moreau, Kerrie L
Format:	Journal Article
Language:	English
Published:	01.11.2022
ISSN:	1522-1539, 1522-1539
Online Access:	Get more information
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