A eukaryotic transcriptional repressor with carboxypeptidase activity

Adipocyte differentiation involves the transcriptional activation of several genes in triglyceride metabolism, including the adipose P2 (aP2 or 422) gene that encodes the adipocyte lipid-binding protein ALBP. Within the mouse aP2 promoter region, the AE-1 sequence functions as either a positive or a...

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Bibliographic Details
Published in:	Nature (London) Vol. 378; no. 6552; pp. 92 - 96
Main Authors:	GONG-PING HE, MUISE, A, WU LI, A, HYO-SUNG RO
Format:	Journal Article
Language:	English
Published:	London Nature Publishing 02.11.1995 Nature Publishing Group
Subjects:	3T3 Cells Adipocytes - cytology Adipocytes - metabolism Amino Acid Sequence Animals Base Sequence Biochemistry Biological and medical sciences Carboxypeptidases - genetics Carboxypeptidases - metabolism Cell Differentiation Chloramphenicol O-Acetyltransferase - genetics Cloning Cloning, Molecular Deoxyribonucleic acid DNA DNA, Complementary Escherichia coli Frameshift Mutation Fundamental and applied biological sciences. Psychology Intercellular Signaling Peptides and Proteins Membrane Proteins - genetics Membrane Proteins - metabolism Metabolism Mice Molecular and cellular biology Molecular genetics Molecular Sequence Data Proteins Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Repressor Proteins - genetics Repressor Proteins - metabolism Rodents Sequence Deletion Transcription. Transcription factor. Splicing. Rna processing Adipocyte Nucleotide sequence Enzyme Rodentia Homology 3T3-Cell line Transcription repressor Carboxypeptidase Cell differentiation Gene expression Vertebrata Mammalia Mouse Enzymatic activity Complementary DNA Gene Fibroblast
ISSN:	0028-0836, 1476-4687
Online Access:	Get full text
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