ALGORITHMS FOR SELECTING BREAKPOINT LOCATIONS TO OPTIMIZE DIVERSITY IN PROTEIN ENGINEERING BY SITE-DIRECTED PROTEIN RECOMBINATION

Protein engineering by site-directed recombination seeks to develop proteins with new or improved function, by accumulating multiple mutations from a set of homologous parent proteins. A library of hybrid proteins is created by recombining the parent proteins at specified breakpoint locations; subse...

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Vydáno v:	Computational Systems Bioinformatics Ročník 6; s. 31 - 40
Hlavní autoři:	Zheng, Wei, Ye, Xiaoduan, Friedman, Alan M., Bailey-Kellogg, Chris
Médium:	Kapitola Journal Article
Jazyk:	angličtina
Vydáno:	United States PUBLISHED BY IMPERIAL COLLEGE PRESS AND DISTRIBUTED BY WORLD SCIENTIFIC PUBLISHING CO 2007
Témata:	Algorithms Base Sequence Genetic Enhancement - methods Genetic Variation - genetics Molecular Sequence Data Mutagenesis, Site-Directed - methods Protein Engineering - methods Proteins - genetics Proteomics Recombinant Proteins - genetics Recombination, Genetic - genetics Sequence Analysis, DNA - methods
ISBN:	1860948723, 9781860948725, 1860948731, 1908979097, 9781860948732, 9781908979094
ISSN:	1752-7791
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