Cav1 inhibits benign skin tumor development in a two-stage carcinogenesis model by suppressing epidermal proliferation

Caveolin-1 (Cav1) is the main protein component of the membrane lipid rafts caveolae. Cav1 serves as a scaffolding protein that compartmentalizes a multitude of signaling molecules and sequesters them in their inactive state. Due to its function in the negative regulation of signal transduction, los...

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Bibliographic Details

Published in:	American journal of translational research Vol. 5; no. 1; p. 80
Main Authors:	Trimmer, Casey, Sotgia, Federica, Lisanti, Michael P, Capozza, Franco
Format:	Journal Article
Language:	English
Published:	United States 01.01.2013
Subjects:	skin skin cancer two stage carcinogenesis Cav1 caveolin
ISSN:	1943-8141, 1943-8141
Online Access:	Get more information
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