Cav1 inhibits benign skin tumor development in a two-stage carcinogenesis model by suppressing epidermal proliferation

Caveolin-1 (Cav1) is the main protein component of the membrane lipid rafts caveolae. Cav1 serves as a scaffolding protein that compartmentalizes a multitude of signaling molecules and sequesters them in their inactive state. Due to its function in the negative regulation of signal transduction, los...

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Vydané v:	American journal of translational research Ročník 5; číslo 1; s. 80
Hlavní autori:	Trimmer, Casey, Sotgia, Federica, Lisanti, Michael P, Capozza, Franco
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.01.2013
Predmet:	skin skin cancer two stage carcinogenesis Cav1 caveolin
ISSN:	1943-8141, 1943-8141
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