Genotypic and phenotypic evidence of T-cell leukemia in a patient successfully treated by interferon-alpha for typical hairy cell leukemia

A 53-year-old man was diagnosed to have typical hairy cell leukemia. Immunophenotyping of frozen splenic tissue showed clonality of hairy cells for mu lambda, confirmed by the corresponding immunoglobulin gene rearrangements. The patient was successfully treated with interferon-alpha (IF-alpha). In...

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Vydané v:	Leukemia Ročník 5; číslo 12; s. 1031
Hlavní autori:	Knecht, H, Sarraj, A, Delacrétaz, F, Bachmann, E, Clément, F
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	England 01.12.1991
Predmet:	Bone Marrow - pathology Clone Cells DNA, Viral - analysis Gene Rearrangement, B-Lymphocyte Gene Rearrangement, T-Lymphocyte Genes, Immunoglobulin Herpesvirus 4, Human - genetics Humans Interferon-alpha - therapeutic use Leukemia, Hairy Cell - pathology Leukemia, Hairy Cell - therapy Leukemia, T-Cell - etiology Middle Aged Neoplasms, Second Primary - etiology Neoplasms, Second Primary - pathology Receptors, Antigen, T-Cell, alpha-beta - genetics Recombinant Proteins
ISSN:	0887-6924
On-line prístup:	Zistit podrobnosti o prístupe
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