Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology

The identification of specific genetic alterations as key oncogenic drivers and the development of targeted therapies are together transforming clinical oncology and creating a pressing need for increased breadth and throughput of clinical genotyping. Next-generation sequencing assays allow the effi...

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Vydáno v:	The Journal of molecular diagnostics : JMD Ročník 17; číslo 3; s. 251
Hlavní autoři:	Cheng, Donavan T, Mitchell, Talia N, Zehir, Ahmet, Shah, Ronak H, Benayed, Ryma, Syed, Aijazuddin, Chandramohan, Raghu, Liu, Zhen Yu, Won, Helen H, Scott, Sasinya N, Brannon, A Rose, O'Reilly, Catherine, Sadowska, Justyna, Casanova, Jacklyn, Yannes, Angela, Hechtman, Jaclyn F, Yao, Jinjuan, Song, Wei, Ross, Dara S, Oultache, Alifya, Dogan, Snjezana, Borsu, Laetitia, Hameed, Meera, Nafa, Khedoudja, Arcila, Maria E, Ladanyi, Marc, Berger, Michael F
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.05.2015
Témata:	DNA - genetics DNA Mutational Analysis - methods Genotype High-Throughput Nucleotide Sequencing - methods Humans Mutation Neoplasms - genetics Paraffin Embedding Reproducibility of Results
ISSN:	1943-7811, 1943-7811
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