Possible Roles for Folic Acid in the Regulation of Trophoblast Invasion and Placental Development in Normal Early Human Pregnancy

In addition to its role in the prevention of neural tube defects, folic acid has many other physiological functions, including cell proliferation, DNA replication, and antioxidant protection. The aim of this study was to determine the role that folic acid has in regulating placental trophoblast deve...

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Bibliographic Details
Published in:	Biology of reproduction Vol. 84; no. 6; pp. 1148 - 1153
Main Authors:	WILLIAMS, Paula J, BULMER, Judith N, INNES, Barbara A, BROUGHTON PIPKIN, Fiona
Format:	Journal Article
Language:	English
Published:	Madison, WI Society for the Study of Reproduction 01.06.2011
Subjects:	Biological and medical sciences Cells, Cultured Embryo Implantation - physiology Female Folic Acid - metabolism Folic Acid - pharmacology Fundamental and applied biological sciences. Psychology Gene Expression Regulation - physiology Humans Matrix Metalloproteinases - genetics Matrix Metalloproteinases - metabolism Placentation Pregnancy Tissue Inhibitor of Metalloproteinases - genetics Tissue Inhibitor of Metalloproteinases - metabolism Trophoblasts - physiology Vertebrates: reproduction Micronutrient Pregnancy Human Trophoblaste Reproduction Placenta Fetal membrane Vitamin Early stage trophoblast Folic acid Invasion
ISSN:	0006-3363, 1529-7268, 1529-7268
Online Access:	Get full text
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