BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer

The BRAF (V600E) mutation is a recognised molecular marker in papillary thyroid cancer (PTC), reported incidence from 30 to 80 %. BRAF(V600E) aberrantly activates the MAPK pathway, a central regulator of cell growth and proliferation. Previous studies have reported conflicting data regarding the imp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	World journal of surgery Jg. 40; H. 7; S. 1618
Hauptverfasser:	Fraser, S, Go, C, Aniss, A, Sidhu, S, Delbridge, L, Learoyd, D, Clifton-Bligh, R, Tacon, L, Tsang, V, Robinson, B, Gill, A J, Sywak, M
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.07.2016
Schlagworte:	Ablation Techniques Adolescent Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Carcinoma - genetics Carcinoma - secondary Carcinoma - surgery Carcinoma, Papillary Child Cohort Studies Disease-Free Survival Female Humans Iodine Radioisotopes - therapeutic use Lymphatic Metastasis Male Middle Aged Mutation Neoplasm Recurrence, Local - genetics Proto-Oncogene Proteins B-raf - analysis Proto-Oncogene Proteins B-raf - genetics Thyroid Cancer, Papillary Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Thyroid Neoplasms - surgery Tumor Burden - genetics Young Adult
ISSN:	1432-2323, 1432-2323
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!