Hepatic vessel segmentation for 3D planning of liver surgery experimental evaluation of a new fully automatic algorithm

The aim of this study was to identify the optimal parameter configuration of a new algorithm for fully automatic segmentation of hepatic vessels, evaluating its accuracy in view of its use in a computer system for three-dimensional (3D) planning of liver surgery. A phantom reproduction of a human li...

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Veröffentlicht in:Academic radiology Jg. 18; H. 4; S. 461
Hauptverfasser: Conversano, Francesco, Franchini, Roberto, Demitri, Christian, Massoptier, Laurent, Montagna, Francesco, Maffezzoli, Alfonso, Malvasi, Antonio, Casciaro, Sergio
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 01.04.2011
Schlagworte:
Algorithms
Hepatectomy - methods
Hepatic Artery - diagnostic imaging
Hepatic Artery - surgery
Hepatic Veins - diagnostic imaging
Hepatic Veins - surgery
Humans
Imaging, Three-Dimensional - methods
Pattern Recognition, Automated - methods
Phantoms, Imaging
Preoperative Care - methods
Reproducibility of Results
Sensitivity and Specificity
Surgery, Computer-Assisted - methods
Tomography, X-Ray Computed - methods
ISSN:1878-4046, 1878-4046
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Zusammenfassung:The aim of this study was to identify the optimal parameter configuration of a new algorithm for fully automatic segmentation of hepatic vessels, evaluating its accuracy in view of its use in a computer system for three-dimensional (3D) planning of liver surgery. A phantom reproduction of a human liver with vessels up to the fourth subsegment order, corresponding to a minimum diameter of 0.2 mm, was realized through stereolithography, exploiting a 3D model derived from a real human computed tomographic data set. Algorithm parameter configuration was experimentally optimized, and the maximum achievable segmentation accuracy was quantified for both single two-dimensional slices and 3D reconstruction of the vessel network, through an analytic comparison of the automatic segmentation performed on contrast-enhanced computed tomographic phantom images with actual model features. The optimal algorithm configuration resulted in a vessel detection sensitivity of 100% for vessels > 1 mm in diameter, 50% in the range 0.5 to 1 mm, and 14% in the range 0.2 to 0.5 mm. An average area overlap of 94.9% was obtained between automatically and manually segmented vessel sections, with an average difference of 0.06 mm(2). The average values of corresponding false-positive and false-negative ratios were 7.7% and 2.3%, respectively. A robust and accurate algorithm for automatic extraction of the hepatic vessel tree from contrast-enhanced computed tomographic volume images was proposed and experimentally assessed on a liver model, showing unprecedented sensitivity in vessel delineation. This automatic segmentation algorithm is promising for supporting liver surgery planning and for guiding intraoperative resections.
Bibliographie:ObjectType-Article-2
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ISSN:1878-4046
1878-4046
DOI:10.1016/j.acra.2010.11.015