Recent developments in the nomenclature, presence, isolation, detection and clinical impact of extracellular vesicles

Summary The research field of extracellular vesicles (EVs), such as microparticles and exosomes, is growing exponentially. The goal of this review is to provide an overview of recent developments relevant to the readers of the Journal of Thrombosis and Haemostasis. We will discuss nomenclature, the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of thrombosis and haemostasis Jg. 14; H. 1; S. 48 - 56
Hauptverfasser: Pol, E., Böing, A. N., Gool, E. L., Nieuwland, R.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: England Elsevier Limited 01.01.2016
Schlagworte:
Blood Platelets - cytology
Body Fluids
Cell-Derived Microparticles - physiology
cell‐derived microparticles
Centrifugation
Chromatography, Gel
Congresses as Topic
exosomes
Exosomes - physiology
Extracellular Vesicles - physiology
Flow Cytometry
Fluorescence
Humans
limit of detection
MicroRNAs - metabolism
secretory vesicles
terminology
Terminology as Topic
flow cytometry
cell-derived microparticles
limit of detection
terminology
exosomes
secretory vesicles
ISSN:1538-7933, 1538-7836, 1538-7836
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Summary The research field of extracellular vesicles (EVs), such as microparticles and exosomes, is growing exponentially. The goal of this review is to provide an overview of recent developments relevant to the readers of the Journal of Thrombosis and Haemostasis. We will discuss nomenclature, the presence of EVs in fluids, methods of isolation and detection, and emerging clinical implications. Although research on EVs has been performed within the ISTH for over a decade, most of the recent research on EVs has been brought together by the International Society on Extracellular Vesicles (ISEV). To achieve an overview of recent developments, the information provided in this review comes not only from publications, but also from latest meetings of the ISEV (April 2015, Washington, DC, USA), the International Society on Advancement of Cytometry (June 2015, Glasgow, UK), and the ISTH (June 2015, Toronto, Canada).
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
ObjectType-Review-3
content type line 23
ISSN:1538-7933
1538-7836
1538-7836
DOI:10.1111/jth.13190