Use of nanobarcodes particles in bioassays

We have developed striped metal nanoparticles, Nanobarcodes particles, which can act as encoded substrates in multiplexed assays. These particles are metallic, encodeable, machine-readable, durable, submicron-sized tags. The power of this technology is that the particles are intrinsically encoded by...

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Veröffentlicht in:Methods in molecular biology (Clifton, N.J.) Jg. 303; S. 73
Hauptverfasser: Freeman, R Griffith, Raju, Paul A, Norton, Scott M, Walton, Ian D, Smith, Patrick C, He, Lin, Natan, Michael J, Sha, Michael Y, Penn, Sharron G
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States 2005
Schlagworte:
Animals
Gene Expression Profiling - methods
Humans
Nanostructures - chemistry
Nanotechnology - methods
Oligonucleotides - chemistry
ISSN:1064-3745
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Zusammenfassung:We have developed striped metal nanoparticles, Nanobarcodes particles, which can act as encoded substrates in multiplexed assays. These particles are metallic, encodeable, machine-readable, durable, submicron-sized tags. The power of this technology is that the particles are intrinsically encoded by virtue of the difference in reflectivity of adjacent metal stripes. This chapter describes protocols for the attachment of biological molecules, and the subsequent use of the Nanobarcodes particles in bioassays.
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:1064-3745
DOI:10.1385/1-59259-901-X:073