Electrically tunable fluidic lens imaging system for laparoscopic fluorescence-guided surgery

The addition of fluorescence guidance in laparoscopic procedures has gained significant interest in recent years, particularly through the use of near infrared (NIR) markers. In this work we present a novel laparoscope camera coupler based on an electrically tunable fluidic lens that permits program...

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Veröffentlicht in:	Biomedical optics express Jg. 8; H. 7; S. 3232 - 3247
Hauptverfasser:	Volpi, Davide, Tullis, Iain D C, Barber, Paul R, Augustyniak, Edyta M, Smart, Sean C, Vallis, Katherine A, Vojnovic, Borivoj
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Optical Society of America 01.07.2017
Schlagworte:	(120.3620) Lens system design (170.0110) Imaging systems (170.6280) Spectroscopy, fluorescence and luminescence (120.4820) Optical systems (170.2150) Endoscopic imaging
ISSN:	2156-7085, 2156-7085
Online-Zugang:	Volltext
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Zusammenfassung:	The addition of fluorescence guidance in laparoscopic procedures has gained significant interest in recent years, particularly through the use of near infrared (NIR) markers. In this work we present a novel laparoscope camera coupler based on an electrically tunable fluidic lens that permits programmable focus control and has desirable achromatic performance from the visible to the NIR. Its use extends the lower working distance limit and improves detection sensitivity, important for work with molecularly targeted fluorescence markers. We demonstrate its superior optical performance in laparoscopic fluorescence-guided surgery. results using a tumor specific molecular probe and a nonspecific NIR dye are presented.
Bibliographie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2156-7085 2156-7085
DOI:	10.1364/BOE.8.003232