Phospholipase D signaling: orchestration by PIP2 and small GTPases

Hydrolysis of phosphatidylcholine by phospholipase D (PLD) leads to the generation of the versatile lipid second messenger, phosphatidic acid (PA), which is involved in fundamental cellular processes, including membrane trafficking, actin cytoskeleton remodeling, cell proliferation and cell survival...

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Bibliographic Details

Published in:	Naunyn-Schmiedeberg's archives of pharmacology Vol. 374; no. 5-6; pp. 399 - 411
Main Authors:	Oude Weernink, Paschal A, López de Jesús, Maider, Schmidt, Martina
Format:	Journal Article
Language:	English
Published:	Germany Springer-Verlag 01.02.2007
Subjects:	Animals Biological Transport Humans Models, Biological Monomeric GTP-Binding Proteins - metabolism Phosphatidylinositol 4,5-Diphosphate - metabolism Phospholipase D - metabolism Phosphotransferases (Alcohol Group Acceptor) - metabolism Review rho GTP-Binding Proteins - metabolism Signal Transduction
ISSN:	0028-1298, 1432-1912
Online Access:	Get full text
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