Advances in the management of cervical lymphadenopathies of unknown primary: advances in diagnostic imaging and surgical modalities and new international staging system

Cervical lymphadenopathies of unknown primary represent 3 % of head and neck cancers. Their diagnostic work up has largely changed in recent years. This review provides an update on diagnostic developments and their potential therapeutic impact. This is a systematic review of the literature. In rece...

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Vydáno v:	Bulletin du cancer Ročník 105; číslo 2; s. 181
Hlavní autoři:	Troussier, Idriss, Klausner, Guillaume, Morinière, Sylvain, Blais, Eivind, Jean-Christophe Faivre, Champion, Ambroise, Geoffrois, Lionnel, Pflumio, Carole, Babin, Emmanuel, Maingon, Philippe, Thariat, Juliette
Médium:	Journal Article
Jazyk:	francouzština
Vydáno:	France 01.02.2018
Témata:	Antineoplastic Agents - therapeutic use Biopsy, Fine-Needle Carcinoma - diagnostic imaging Carcinoma - secondary Carcinoma - therapy Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - therapy Carcinoma, Squamous Cell - virology Chemoradiotherapy Combined Modality Therapy - methods Head and Neck Neoplasms - diagnostic imaging Head and Neck Neoplasms - pathology Head and Neck Neoplasms - therapy Head and Neck Neoplasms - virology Humans Lymphatic Metastasis - diagnostic imaging Lymphatic Metastasis - pathology Neck Neoplasm Staging - methods Neoplasms, Unknown Primary - diagnostic imaging Neoplasms, Unknown Primary - pathology Neoplasms, Unknown Primary - therapy Papillomaviridae - isolation & purification Tonsillectomy Robotic surgery Lymphadenopathy Adénopathie cervicale Curage Staging Classification Cancer primitif inconnu Head and neck Human papilloma virus Chirurgie robotique Unknown primary Neck dissection
ISSN:	1769-6917, 1769-6917
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Shrnutí:	Cervical lymphadenopathies of unknown primary represent 3 % of head and neck cancers. Their diagnostic work up has largely changed in recent years. This review provides an update on diagnostic developments and their potential therapeutic impact. This is a systematic review of the literature. In recent years, changes in epidemiology-based prognostic factors such as human papilloma virus (HPV) cancers, advances in imaging and minimally invasive surgery have been integrated in the management of cervical lymphadenopathies of unknown primary. In particular, systematic use of PET scanner and increasing practice of robotic or laser surgery have contributed to increasing detection rate of primary cancers. These allow more adapted and personalized treatments. The impact of changes in the eighth TNM staging system is discussed. The management of cervical lymphadenopathies of unknown primary cancer has changed significantly in the last 10 years. On the other hand, practice changes will have to be assessed.
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 ObjectType-Undefined-4
ISSN:	1769-6917 1769-6917
DOI:	10.1016/j.bulcan.2017.11.009