Intermediate-affinity interleukin-2 receptor expression predicts CD56(bright) natural killer cell expansion after daclizumab treatment in the CHOICE study of patients with multiple sclerosis

The objective of this study was to evaluate whether interleukin-2 (IL-2) receptor expression on CD56(bright) natural killer (NK) cells predicted CD56(bright) NK cell expansion and therapeutic response to daclizumab (DAC) in multiple sclerosis (MS). DAC exposure, CD56(bright) NK cell counts, IL-2 rec...

Celý popis

Podrobná bibliografie

Vydáno v:	Multiple sclerosis Ročník 17; číslo 12; s. 1441
Hlavní autoři:	Sheridan, James P, Zhang, Ying, Riester, Katherine, Tang, Meina T, Efros, Lyubov, Shi, Jia, Harris, Jeffrey, Vexler, Vladimir, Elkins, Jacob S
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England 01.12.2011
Témata:	Antibodies, Monoclonal, Humanized - therapeutic use CD56 Antigen - analysis Cell Proliferation - drug effects Humans Immunoglobulin G - therapeutic use Interleukin-2 Receptor alpha Subunit - metabolism Interleukin-2 Receptor beta Subunit - metabolism Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Multiple Sclerosis - drug therapy Multiple Sclerosis - immunology Multiple Sclerosis - metabolism
ISSN:	1477-0970, 1477-0970
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!