Nuclear transfer and reprogramming in fish

As an important sub-field in the study of animal cloning, fish nuclear transfer was first established in the early 1960s by Chinese embryologists. Due to its advantages, zebrafish has become a unique animal model to study the mystery of reprogramming in nuclear transfer. This article summarizes the...

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Vydáno v:Yíchuán Ročník 35; číslo 4; s. 433
Hlavní autoři: Wang, Xue-Geng, Zhu, Zuo-Yan, Sun, Yong-Hua, Zhao, Jue
Médium: Journal Article
Jazyk:čínština
Vydáno: China 01.04.2013
Témata:
Animals
Cellular Reprogramming
Embryo, Nonmammalian - embryology
Embryo, Nonmammalian - metabolism
Nuclear Transfer Techniques
Zebrafish - embryology
Zebrafish - genetics
ISSN:0253-9772
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Shrnutí:As an important sub-field in the study of animal cloning, fish nuclear transfer was first established in the early 1960s by Chinese embryologists. Due to its advantages, zebrafish has become a unique animal model to study the mystery of reprogramming in nuclear transfer. This article summarizes the history and current situation in fish nuclear transfer technology and discusses the factors that may influence the development of the cloned embryos. A comprehensive understand-ing of the mechanism for epigenetic modification following nuclear transfer, such as genomic DNA methylation and histone acetylation and/or methylation, will likely increase the success rate and eventually lead to the future freedom of cloning technique.
Bibliografie:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
ObjectType-Review-3
content type line 23
ISSN:0253-9772
DOI:10.3724/SP.J.1005.2013.00433