Advances in the clinical management of dentin hypersensitivity: a review of recent evidence for the efficacy of dentifrices in providing instant and lasting relief

This paper summarizes the current state of knowledge of the epidemiology, etiology, and clinical management of dentin hypersensitivity, with special emphasis on the evidence for the effectiveness of commonly available sensitivity relief toothpastes. It reviews the scientific and clinical research va...

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Bibliographic Details
Published in:The Journal of clinical dentistry Vol. 22; no. 4; p. 100
Main Author: Cummins, D
Format: Journal Article
Language:English
Published: United States 2011
Subjects:
Acetates - therapeutic use
Arginine - administration & dosage
Arginine - therapeutic use
Calcium Carbonate - administration & dosage
Calcium Carbonate - therapeutic use
Dentin Desensitizing Agents - administration & dosage
Dentin Desensitizing Agents - therapeutic use
Dentin Sensitivity - drug therapy
Drug Combinations
Fluorides - administration & dosage
Fluorides - therapeutic use
Humans
Potassium - therapeutic use
Randomized Controlled Trials as Topic
Strontium - therapeutic use
Toothpastes - therapeutic use
ISSN:0895-8831
Online Access:Get more information
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Summary:This paper summarizes the current state of knowledge of the epidemiology, etiology, and clinical management of dentin hypersensitivity, with special emphasis on the evidence for the effectiveness of commonly available sensitivity relief toothpastes. It reviews the scientific and clinical research validating the effectiveness of a recently introduced toothpaste containing 8.0% arginine and calcium carbonate, known as Pro-Argin technology, including clinical evidence for the superior efficacy of this toothpaste versus potassium-based sensitivity relief toothpastes. It critiques recently published studies on a strontium-based sensitivity relief toothpaste. Finally, it summarizes new clinical data from three parallel, randomized, head-to-head studies comparing the efficacy of a toothpaste containing 8.0% arginine and calcium carbonate (positive control) to a strontium-based sensitivity relief toothpaste (test) in delivering superior instant and lasting sensitivity relief. The results of these new clinical studies clearly support the conclusions that 1) a toothpaste containing 8.0% arginine and calcium carbonate provides superior efficacy with respect to both immediate and lasting relief of dentin hypersensitivity compared to a toothpaste containing 8% strontium acetate, and 2) a toothpaste containing 8% strontium acetate is no more effective in providing immediate relief of dentin hypersensitivity than a regular fluoride toothpaste.
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ISSN:0895-8831