The hormonal and morphological events of stimulated cycles in an in vitro fertilisation programme

A better understanding of the physiological processes involved in the stimulated cycle for successful harvesting of mature eggs in an in vitro fertilisation programme is a prerequisite for obtaining good pregnancy results. The hormonal levels of oestradiol, luteinising hormone (LH) and follicle-stim...

Full description

Saved in:
Bibliographic Details
Published in:South African medical journal Vol. 71; no. 4; p. 227
Main Authors: van der Merwe, J V, Grace, A, Snyman, E
Format: Journal Article
Language:English
Published: South Africa 21.02.1987
Subjects:
Adult
Chorionic Gonadotropin - administration & dosage
Chorionic Gonadotropin - blood
Chorionic Gonadotropin - pharmacology
Clomiphene - administration & dosage
Clomiphene - pharmacology
Estradiol - blood
Female
Follicle Stimulating Hormone - blood
Follicular Phase
Humans
Luteinizing Hormone - blood
Menstrual Cycle - drug effects
Ovarian Follicle - physiology
Ovulation Detection
Ovulation Induction - methods
Time Factors
ISSN:0256-9574
Online Access:Get more information
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A better understanding of the physiological processes involved in the stimulated cycle for successful harvesting of mature eggs in an in vitro fertilisation programme is a prerequisite for obtaining good pregnancy results. The hormonal levels of oestradiol, luteinising hormone (LH) and follicle-stimulating hormone correlated with ultrasonographic studies of follicular growth, were followed during an in vitro fertilisation cycle giving an overall pregnancy rate of 32% per transfer procedure. The combined use of clomiphene citrate (Clomid; Mer-National) and human post-menopausal gonadotrophin (Pergonal; Script Intal) produces an average of 5.96 follicles per patient. Human chorionic gonadotrophin (HCG) was given prior to the oestrogen peak and no spontaneous LH peak occurred before the day of the HCG injection. Timing of this injection needs to be synchronised with definite hormonal and ultrasonography values.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0256-9574