A comprehensive evaluation of popular proteomics software workflows for label-free proteome quantification and imputation

Abstract Label-free mass spectrometry (MS) has developed into an important tool applied in various fields of biological and life sciences. Several software exist to process the raw MS data into quantified protein abundances, including open source and commercial solutions. Each software includes a se...

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Veröffentlicht in:	Briefings in bioinformatics Jg. 19; H. 6; S. 1344 - 1355
Hauptverfasser:	Välikangas, Tommi, Suomi, Tomi, Elo, Laura L
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	England Oxford University Press 27.11.2018 Oxford Publishing Limited (England)
Schlagworte:	Algorithms Chromatography, Liquid - methods Computer programs computer software data collection Data processing Datasets Filtration Freeware gene expression regulation information processing Information systems Least squares Mass spectrometry Mass Spectrometry - methods Mass spectroscopy Proteins proteome Proteome - analysis Proteomics Regression analysis Software Workflow evaluation differential expression proteomics software workflow imputation logarithmic fold change
ISSN:	1467-5463, 1477-4054, 1477-4054
Online-Zugang:	Volltext
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