Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform

Due to the increasing throughput of current DNA sequencing instruments, sample multiplexing is necessary for making economical use of available sequencing capacities. A widely used multiplexing strategy for the Illumina Genome Analyzer utilizes sample-specific indexes, which are embedded in one of t...

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Bibliographic Details

Published in:	Nucleic acids research Vol. 40; no. 1; p. e3
Main Authors:	Kircher, Martin, Sawyer, Susanna, Meyer, Matthias
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.01.2012
Subjects:	Gene Library High-Throughput Nucleotide Sequencing - methods Methods Online Reproducibility of Results Sequence Analysis, DNA - methods
ISSN:	0305-1048, 1362-4962, 1362-4962
Online Access:	Get full text
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