Toward unraveling molecular grammars for dsRNA-binding proteins: substrate recognition to binding mechanisms

Long double-stranded RNAs (dsRNAs) are recognized by innate immune response proteins, thereby initiating the integrated stress response. As these RNAs adopt an A-form helical structure, immune sensors recognize dsRNAs primarily based on their structural features, such as the length of the doublestra...

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Veröffentlicht in:	BMB reports Jg. 58; H. 11; S. 451
Hauptverfasser:	Jeon, Jaemin, Kim, Yoosik
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Korea (South) 01.11.2025
Schlagworte:	Humans Protein Binding RNA, Double-Stranded - chemistry RNA, Double-Stranded - genetics RNA, Double-Stranded - metabolism RNA-Binding Proteins - chemistry RNA-Binding Proteins - genetics RNA-Binding Proteins - metabolism
ISSN:	1976-670X, 1976-670X
Online-Zugang:	Weitere Angaben
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