Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients

Human skin acts as a primary barrier between the body and its environment. Crucial for this skin barrier function is the lipid matrix in the outermost layer of the skin, the stratum corneum (SC). Two of its functions are (1) to prevent excessive water loss through the epidermis and (2) to avoid that...

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Bibliographic Details
Published in:	Current problems in dermatology Vol. 49; pp. 8 - 26
Main Authors:	van Smeden, Jeroen, Bouwstra, Joke A
Format:	Journal Article
Language:	English
Published:	Switzerland 01.01.2016
Subjects:	Ceramides - metabolism Cholesterol - metabolism Dermatitis, Atopic - metabolism Dermatitis, Atopic - physiopathology Epidermis - chemistry Epidermis - metabolism Epidermis - physiology Fatty Acids - metabolism Healthy Volunteers Humans Intermediate Filament Proteins - genetics Lipid Metabolism - physiology Lipids - analysis Lipids - biosynthesis Mutation Permeability Skin Physiological Phenomena - genetics Water Loss, Insensible - physiology
ISSN:	1662-2944
Online Access:	Get more information
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