Tests for detection of rare variants and gene-environment interaction in cohort and twin family studies

Complex diseases are caused by a combination of environmental and genetic factors. While we have estimated that genetic factors explain a large proportion of variance in many of these diseases, current strategies using only the genotyped common variants (CVs) have failed to explain all of this herit...

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Bibliographische Detailangaben
1. Verfasser: Coombes, Brandon J
Format: Dissertation
Sprache:Englisch
Veröffentlicht: ProQuest Dissertations & Theses 01.01.2016
Schlagworte:
ISBN:1369354908, 9781369354904
Online-Zugang:Volltext
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