MRGPRX2 is negatively targeted by SCF and IL‐4 to diminish pseudo‐allergic stimulation of skin mast cells in culture

MRGPRX2 was recently uncovered as the “missing link” in clinically relevant mast cell (MC) activation explaining previously puzzling phenomena. It is the receptor for various endogenous ligands and exogenous compounds alike, whose binding evokes rapid degranulation much like allergen‐mediated exocyt...

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Vydané v:	Experimental dermatology Ročník 27; číslo 11; s. 1298 - 1303
Hlavní autori:	Babina, Magda, Wang, Zhao, Artuc, Metin, Guhl, Sven, Zuberbier, Torsten
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Denmark Wiley Subscription Services, Inc 01.11.2018
Predmet:	Allergens allergy Cell activation Cell culture Degranulation Exocytosis Hypersensitivity Mast cells MRGPRX2 pseudo‐allergy SCF Skin allergy pseudo-allergy mast cells MRGPRX2 SCF
ISSN:	0906-6705, 1600-0625, 1600-0625
On-line prístup:	Získať plný text
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