MODELING STABILIZING SELECTION: EXPANDING THE ORNSTEIN—UHLENBECK MODEL OF ADAPTIVE EVOLUTION
Comparative methods used to study patterns of evolutionary change in a continuous trait on a phylogeny range from Brownian motion processes to models where the trait is assumed to evolve according to an Ornstein—Uhlenbeck (OU) process. Although these models have proved useful in a variety of context...
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| Vydáno v: | Evolution Ročník 66; číslo 8; s. 2369 - 2383 |
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| Hlavní autoři: | , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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Malden, USA
Wiley Subscription Services, Inc
01.08.2012
Blackwell Publishing Inc Oxford University Press |
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| ISSN: | 0014-3820, 1558-5646, 1558-5646 |
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| Abstract | Comparative methods used to study patterns of evolutionary change in a continuous trait on a phylogeny range from Brownian motion processes to models where the trait is assumed to evolve according to an Ornstein—Uhlenbeck (OU) process. Although these models have proved useful in a variety of contexts, they still do not cover all the scenarios biologists want to examine. For models based on the OU process, model complexity is restricted in current implementations by assuming that the rate of stochastic motion and the strength of selection do not vary among selective regimes. Here, we expand the OU model of adaptive evolution to include models that variously relax the assumption of a constant rate and strength of selection. In its most general form, the methods described here can assign each selective regime a separate trait optimum, a rate of stochastic motion parameter, and a parameter for the strength of selection. We use simulations to show that our models can detect meaningful differences in the evolutionary process, especially with larger sample sizes. We also illustrate our method using an empirical example of genome size evolution within a large flowering plant clade. |
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| AbstractList | Comparative methods used to study patterns of evolutionary change in a continuous trait on a phylogeny range from Brownian motion processes to models where the trait is assumed to evolve according to an Ornstein-Uhlenbeck (OU) process. Although these models have proved useful in a variety of contexts, they still do not cover all the scenarios biologists want to examine. For models based on the OU process, model complexity is restricted in current implementations by assuming that the rate of stochastic motion and the strength of selection do not vary among selective regimes. Here, we expand the OU model of adaptive evolution to include models that variously relax the assumption of a constant rate and strength of selection. In its most general form, the methods described here can assign each selective regime a separate trait optimum, a rate of stochastic motion parameter, and a parameter for the strength of selection. We use simulations to show that our models can detect meaningful differences in the evolutionary process, especially with larger sample sizes. We also illustrate our method using an empirical example of genome size evolution within a large flowering plant clade. [PUBLICATION ABSTRACT] Comparative methods used to study patterns of evolutionary change in a continuous trait on a phylogeny range from Brownian motion processes to models where the trait is assumed to evolve according to an Ornstein-Uhlenbeck (OU) process. Although these models have proved useful in a variety of contexts, they still do not cover all the scenarios biologists want to examine. For models based on the OU process, model complexity is restricted in current implementations by assuming that the rate of stochastic motion and the strength of selection do not vary among selective regimes. Here, we expand the OU model of adaptive evolution to include models that variously relax the assumption of a constant rate and strength of selection. In its most general form, the methods described here can assign each selective regime a separate trait optimum, a rate of stochastic motion parameter, and a parameter for the strength of selection. We use simulations to show that our models can detect meaningful differences in the evolutionary process, especially with larger sample sizes. We also illustrate our method using an empirical example of genome size evolution within a large flowering plant clade.Comparative methods used to study patterns of evolutionary change in a continuous trait on a phylogeny range from Brownian motion processes to models where the trait is assumed to evolve according to an Ornstein-Uhlenbeck (OU) process. Although these models have proved useful in a variety of contexts, they still do not cover all the scenarios biologists want to examine. For models based on the OU process, model complexity is restricted in current implementations by assuming that the rate of stochastic motion and the strength of selection do not vary among selective regimes. Here, we expand the OU model of adaptive evolution to include models that variously relax the assumption of a constant rate and strength of selection. In its most general form, the methods described here can assign each selective regime a separate trait optimum, a rate of stochastic motion parameter, and a parameter for the strength of selection. We use simulations to show that our models can detect meaningful differences in the evolutionary process, especially with larger sample sizes. We also illustrate our method using an empirical example of genome size evolution within a large flowering plant clade. Comparative methods used to study patterns of evolutionary change in a continuous trait on a phylogeny range from Brownian motion processes to models where the trait is assumed to evolve according to an Ornstein–Uhlenbeck (OU) process. Although these models have proved useful in a variety of contexts, they still do not cover all the scenarios biologists want to examine. For models based on the OU process, model complexity is restricted in current implementations by assuming that the rate of stochastic motion and the strength of selection do not vary among selective regimes. Here, we expand the OU model of adaptive evolution to include models that variously relax the assumption of a constant rate and strength of selection. In its most general form, the methods described here can assign each selective regime a separate trait optimum, a rate of stochastic motion parameter, and a parameter for the strength of selection. We use simulations to show that our models can detect meaningful differences in the evolutionary process, especially with larger sample sizes. We also illustrate our method using an empirical example of genome size evolution within a large flowering plant clade. |
| Author | Jhwueng, Dwueng-Chwuan Boettiger, Carl O'Meara, Brian C. Beaulieu, Jeremy M. |
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| References | 2004; 21 2007; 17 1938; 25 2004; 164 2009; 63 2010; 59 1995; 90 2010 2006; 55 2002; 56 1999; 48 2006; 37 1996; 50 2006; 273 1996; 93 2009; 276 2007 2008; 57 2011; 98 2008; 105 1992; 35 2003; 19 2002 2008; 322 2007; 56 1974; 19 2006; 60 2010; 64 1995; 82 1997; 51 2007; 315 2006; 22 2004; 58 1997; 14 1975; 29 2005; 7 2011; 66 2009; 9 2011; 65 2009; 161 2008; 179 2008; 275 1989; 36 2006; 167 2010; 6 1981; 31 |
| References_xml | – volume: 17 start-page: 594 year: 2007 end-page: 601 article-title: The mode and tempo of genome size evolution in eukaryotes publication-title: Genome Res. – volume: 315 start-page: 1812 year: 2007 article-title: Floral gigantism in Rafflesiaceae publication-title: Science – volume: 48 start-page: 612 year: 1999 end-page: 622 article-title: The maximum likelihood approach to reconstructing ancestral character states of discrete characters on phylogenies publication-title: Syst. Biol. – volume: 64 start-page: 2385 year: 2010 end-page: 2396 article-title: Early bursts of body size and shape evolution are rare in comparative data publication-title: Evolution – volume: 93 start-page: 10274 year: 1996 end-page: 10279 article-title: Substitution rate comparisons between grasses and palms: synonymous rate differences at the nuclear gene Adh parallel rate differences at the plastid gene rbcL publication-title: Proc. Natl. Acad. Sci. USA – volume: 37 start-page: 187 year: 2006 end-page: 214 article-title: Some evolutionary consequences of being a tree publication-title: Annu. Rev. Ecol. Evol. Syst. – volume: 322 start-page: 86 year: 2008 end-page: 89 article-title: Rates of molecular evolution are linked to life history in flowering plants publication-title: Science – volume: 29 start-page: 707 year: 1975 end-page: 722 article-title: Biological considerations of the marsupial‐placentaal dichotomy publication-title: Evolution – volume: 57 start-page: 562 year: 2008 end-page: 573 article-title: The role of geography and ecological opportunity in the diversification of day geckos (Phelsuma) publication-title: Syst. Biol. – volume: 21 start-page: 1123 year: 2004 end-page: 1133 article-title: Bayesian phylogenetic model selection using reversible jump Markov Chain Monte Carlo publication-title: Mol. Biol. Evol. – volume: 98 start-page: 1 year: 2011 end-page: 12 article-title: Understanding angiosperm diversification using small and large phylogenetic trees publication-title: Am. J. Bot. – volume: 105 start-page: 11549 year: 2008 end-page: 11555 article-title: A phylogenetic perspective on the distribution of plant species publication-title: Proc. Natl. Acad. Sci. USA – volume: 22 start-page: 2688 year: 2006 end-page: 2690 article-title: Maximum likelihood‐based phylogenetic analyses with thousands of taxa and mixed models publication-title: Bioinformatics – volume: 167 start-page: 808 year: 2006 end-page: 825 article-title: Bayesian analysis of correlated evolution of discrete characters by reversible‐jump Markov Chain Monte Carlo publication-title: Am. Nat. – year: 2010 article-title: On the tempo of genome size evolution in angiosperms publication-title: J. Bot. – volume: 55 start-page: 818 year: 2006 end-page: 836 article-title: Phylogenetic supermatrix analysis of GenBank sequences from 2228 papilionoid legumes publication-title: Syst. Biol. – volume: 19 start-page: 301 year: 2003 end-page: 302 article-title: r8s: inferring absolute rates of molecular evolution and divergence times in the absence of a molecular clock publication-title: Bioinformatics – volume: 60 start-page: 922 year: 2006 end-page: 933 article-title: Testing for different rates of continuous trait evolution publication-title: Evolution – volume: 7 start-page: 449 year: 2005 end-page: 458 article-title: Climate and growth form: the consequences for genome size in plants publication-title: Plant Biol. – volume: 275 start-page: 2749 year: 2008 end-page: 2757 article-title: Testing the island effect in adaptive radiation: rates and patterns of morphological diversification in Caribbean and mainland Anolis lizards publication-title: Proc. R. Soc. B – volume: 273 start-page: 1619 year: 2006 end-page: 1624 article-title: Comparative analyses of the influence of developmental mode on phenotypic diversification rates in shorebirds publication-title: Proc. R. Soc. Lond. B – volume: 59 start-page: 42 year: 2010 end-page: 58 article-title: Sparse supermatrices for phylogenetic inference: taxonomy, alignment, rogue taxa, and the phylogeny of living turtles publication-title: Syst. Biol. – volume: 31 start-page: 573 year: 1981 end-page: 577 article-title: Why are there so many species of flowering plants? publication-title: Bioscience – volume: 179 start-page: 975 year: 2008 end-page: 986 article-title: Genome size is a strong predictor of cell size and stomatal density in angiosperms publication-title: New Phytol. – volume: 58 start-page: 2353 year: 2004 end-page: 2370 article-title: Constraints on the morphological evolution of marsupial shoulder girdles publication-title: Evolution – volume: 6 start-page: 2532 year: 2010 end-page: 2537 article-title: Phylogenetic analyses reveal the shady history of C4 grasses publication-title: Proc. Natl. Acad. Sci. USA – volume: 65 start-page: 3578 year: 2011 end-page: 3589 article-title: AUTEUR: a novel comparative method for modeling shifts in the rate of character evolution on trees publication-title: Evolution – volume: 164 start-page: 683 year: 2004 end-page: 695 article-title: Phylogenetic comparative analysis: a modeling approach for adaptive evolution publication-title: Am. Nat. – year: 2007 – volume: 14 start-page: 769 year: 1997 end-page: 777 article-title: Comparisons of the molecular evolutionary process at rbcL and ndhF in the grass family (Poaceae) publication-title: Mol. Biol. Evol. – volume: 51 start-page: 1341 year: 1997 end-page: 1351 article-title: Stabilizing selection and the comparative analysis of adaptation publication-title: Evolution – volume: 57 start-page: 335 year: 2008 end-page: 346 article-title: The PhyLoTA browser: processing GenBank for molecular phylogenetics research publication-title: Syst. Biol. – year: 2010 – volume: 36 start-page: 227 year: 1989 end-page: 249 article-title: The tortoise and the hare: ecology of angiosperm dominance and gymnosperm persistence publication-title: Biol. J. Linn. Soc. – volume: 9 start-page: 1 year: 2009 end-page: 12 article-title: Mega‐phylogeny approach for comparative biology: an alternative to supertree and supermatrix approaches publication-title: BMC Evol. Biol. – volume: 25 start-page: 189 year: 1938 end-page: 198 article-title: Cytological characteristics associated with different growth habits in dicotyledons publication-title: Am. J. Bot. – volume: 19 start-page: 716 year: 1974 end-page: 723 article-title: A new look at the statistical model identification publication-title: IEEE Trans. Automat. Contr. – year: 2002 – volume: 22 start-page: 63 year: 2006 end-page: 75 article-title: Multigene analyses of monocot relationships: a summary publication-title: Aliso – volume: 35 start-page: 292 year: 1992 end-page: 303 article-title: Relative rates of nucleotide substitution at the rbcL locus of monocotyledonous plants publication-title: J. Mol. Evol. – volume: 82 start-page: 711 year: 1995 end-page: 732 article-title: Reversible jump Markov chain monte carlo computation and Bayesian model determination publication-title: Biometrika – volume: 50 start-page: 1404 year: 1996 end-page: 1417 article-title: Translating between microevolutionary process and macroevolutionary patterns: the correlation structure of interspecific data publication-title: Evolution – volume: 66 start-page: 135 year: 2011 end-page: 146 article-title: A new phylogenetic method for identifying exceptional phenotypic diversification publication-title: Evolution – volume: 56 start-page: 822 year: 2007 end-page: 846 article-title: Towards a phylogenetic nomenclature of Tracheophyta publication-title: Taxon – volume: 90 start-page: 773 year: 1995 end-page: 795 article-title: Bayes factors publication-title: J. Am. Stat. Assoc. – volume: 161 start-page: 105 year: 2009 end-page: 121 article-title: An update of the Angiosperm Phylogeny Group classification for the orders and families of flowering plants: APG III publication-title: Bot. J. Linn. Soc – volume: 276 start-page: 4345 year: 2009 end-page: 4352 – volume: 56 start-page: 1352 year: 2002 end-page: 1361 article-title: Age at maturity and diversification in woody angiosperms publication-title: Evolution – volume: 63 start-page: 1557 year: 2009 end-page: 1573 article-title: Piscivory limits diversification of feeding morphology in centrarchid fishes publication-title: Evolution |
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| Title | MODELING STABILIZING SELECTION: EXPANDING THE ORNSTEIN—UHLENBECK MODEL OF ADAPTIVE EVOLUTION |
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