Amyloid-like p53 as prognostic biomarker in serous ovarian cancer—a study of the OVCAD consortium

TP53 is the most commonly mutated gene in cancer and has been shown to form amyloid-like aggregates, similar to key proteins in neurodegenerative diseases. Nonetheless, the clinical implications of p53 aggregation remain unclear. Here, we investigated the presence and clinical relevance of p53 aggre...

Full description

Saved in:

Bibliographic Details
Published in:	Oncogene Vol. 42; no. 33; pp. 2473 - 2484
Main Authors:	Heinzl, Nicole, Maritschnegg, Elisabeth, Koziel, Katarzyna, Schilhart-Wallisch, Christine, Heinze, Georg, Yang, Wei-Lei, Bast, Robert C., Sehouli, Jalid, Braicu, Elena I., Vergote, Ignace, Van Gorp, Toon, Mahner, Sven, Paspalj, Valentina, Grimm, Christoph, Obermayr, Eva, Schuster, Eva, Holzer, Barbara, Rousseau, Frederic, Schymkowitz, Joost, Concin, Nicole, Zeillinger, Robert
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 11.08.2023 Nature Publishing Group
Subjects:	13/1 13/2 13/51 14 14/63 45/29 631/67/1517/1709 692/53/2422 82 Amyloid Apoptosis Autoantibodies Cell Biology Cytotoxicity Human Genetics Immune response Internal Medicine Medical prognosis Medicine Medicine & Public Health Missense mutation Neurodegenerative diseases Oncology Ovarian cancer p53 Protein Survival
ISSN:	0950-9232, 1476-5594, 1476-5594
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!