Discovery and characterization of highly immunogenic and broadly recognized mimics of the HIV‐1 CTL epitope Gag77–85

Human immunodeficiency virus (HIV)‐specific cytotoxic T lymphocytes (CTL) play an important role in HIV infection. Given the viral genetic diversity, the selection of suitable antigens and epitope variants will be important in the design of an effective vaccine. We have previously shown that combina...

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Vydáno v:	European journal of immunology Ročník 35; číslo 5; s. 1428 - 1437
Hlavní autoři:	Boggiano, César, Moya, Rosa, Pinilla, Clemencia, Bihl, Florian, Brander, Christian, Sidney, John, Sette, Alessandro, Blondelle, Sylvie E.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Weinheim WILEY‐VCH Verlag 01.05.2005
Témata:	Amino Acid Sequence Animals Cross Reactions CTL epitope Cytotoxic T lymphocytes env Gene Products, Human Immunodeficiency Virus Epitopes, T-Lymphocyte - immunology Escape variant Gene Products, gag - chemistry Gene Products, gag - immunology HIV HIV Antigens - immunology HIV Infections - immunology HIV-1 - immunology Humans Mice Mice, Transgenic Molecular Mimicry - immunology Molecular Sequence Data Peptide Fragments - chemistry Peptide Fragments - immunology Peptide Library T-Lymphocytes, Cytotoxic - immunology
ISSN:	0014-2980, 1521-4141
On-line přístup:	Získat plný text
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