Automated volumetry and regional thickness analysis of hippocampal subfields and medial temporal cortical structures in mild cognitive impairment

We evaluate a fully automatic technique for labeling hippocampal subfields and cortical subregions in the medial temporal lobe in in vivo 3 Tesla MRI. The method performs segmentation on a T2‐weighted MRI scan with 0.4 × 0.4 × 2.0 mm3 resolution, partial brain coverage, and oblique orientation. Hipp...

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Bibliographic Details
Published in:	Human brain mapping Vol. 36; no. 1; pp. 258 - 287
Main Authors:	Yushkevich, Paul A., Pluta, John B., Wang, Hongzhi, Xie, Long, Ding, Song-Lin, Gertje, Eske C., Mancuso, Lauren, Kliot, Daria, Das, Sandhitsu R., Wolk, David A.
Format:	Journal Article
Language:	English
Published:	United States Blackwell Publishing Ltd 01.01.2015 John Wiley & Sons, Inc John Wiley and Sons Inc
Subjects:	Algorithms Alzheimer's disease Automatic Data Processing biomarker Brain Mapping Brodmann area 35 Cognitive Dysfunction - pathology cornu ammonis entorhinal cortex Female hippocampus Hippocampus - pathology Humans Image Processing, Computer-Assisted Learning - physiology Magnetic Resonance Imaging Male perirhinal cortex segmentation Temporal Lobe - pathology cornu ammonis magnetic resonance imaging hippocampus entorhinal cortex segmentation biomarker Alzheimer's disease Brodmann area 35 perirhinal cortex
ISSN:	1065-9471, 1097-0193, 1097-0193
Online Access:	Get full text
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