Beyond 'cure' and 'treatment success': quality of life of patients with multidrug-resistant tuberculosis

Two drug-resistant tuberculosis (DR-TB) sites (MSF Clinic, Jupiter Hospital) in Mumbai, India. To assess health-related quality of life (HRQoL) and associated factors among DR-TB patients and explore their perspectives about HRQoL. We used a mixed-methods design: a quantitative cross-sectional quest...

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Vydáno v:The international journal of tuberculosis and lung disease Ročník 23; číslo 1; s. 73
Hlavní autoři: Laxmeshwar, C, Stewart, A G, Dalal, A, Kumar, A M V, Kalaiselvi, S, Das, M, Gawde, N, Thi, S S, Isaakidis, P
Médium: Journal Article
Jazyk:angličtina
Vydáno: France 01.01.2019
Témata:
Adult
Cross-Sectional Studies
Female
Humans
India
Interviews as Topic
Male
Middle Aged
Psychometrics
Quality of Life
Surveys and Questionnaires
Treatment Outcome
Tuberculosis, Multidrug-Resistant - psychology
Tuberculosis, Multidrug-Resistant - therapy
Young Adult
India
ISSN:1815-7920, 1815-7920
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Shrnutí:Two drug-resistant tuberculosis (DR-TB) sites (MSF Clinic, Jupiter Hospital) in Mumbai, India. To assess health-related quality of life (HRQoL) and associated factors among DR-TB patients and explore their perspectives about HRQoL. We used a mixed-methods design: a quantitative cross-sectional questionnaire (the World Health Organization's Quality of Life Brief Questionnaire [WHOQoL-BREF]); and qualitative in-depth interviews for purposively selected patients. Assessments were conducted between April and November 2016. Ninety-five patients completed WHOQoL-BREF; 12 were interviewed. The psychological and physical health domains were the most affected (mean scores 56.2 ± standard deviation [SD] 18.3, and 56.5 ± SD 15.1, respectively; maximum 100). The social relations and environmental domains mean scores were respectively 68.6 (SD ±21.1) and 60.3 (SD ±15.9). Loss of jobs due to TB adversely affected the social relations and environmental domains. Qualitative analysis showed that support was the most important theme affecting quality of life. Other themes were physical factors (e.g., treatment adverse events), psychological factors (e.g., depression), social functioning (e.g., fear of stigmatisation) and environmental factors (e.g., health systems). HRQoL was lower among study participants, but not as low as previously reported among TB patients. Support was the main factor that positively affected HRQoL, although both disease and treatment were physically and socially challenging.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1815-7920
1815-7920
DOI:10.5588/ijtld.18.0149