Electrical conductivity imaging of lower extremities using MREIT: Postmortem swine and in vivo human experiments

Cross-sectional conductivity images of lower extremities were reconstructed using Magnetic Resonance Electrical Impedance Tomography (MREIT) techniques. Carbon-hydrogel electrodes were adopted for postmortem swine and in vivo human imaging experiments. Due to their large surface areas and good conta...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Ročník 2008; s. 5830 - 5833
Hlavní autoři: Woo, Eung Je, Kim, Hyung Joong, Minhas, Atul S., Kim, Young Tae, Jeong, Woo Chul, Kwon, O. Jung
Médium: Konferenční příspěvek Journal Article
Jazyk:angličtina
Vydáno: United States IEEE 01.01.2008
Témata:
Adult
Animals
Conductivity
Current density
Electric Conductivity
Electrodes
Humans
Image reconstruction
Imaging
Legged locomotion
Lower Extremity - anatomy & histology
Lower Extremity - physiology
Magnetic resonance
Magnetic Resonance Imaging
Male
Middle Aged
Plethysmography, Impedance - methods
Swine
Young Adult
ISBN:9781424418145, 1424418143
ISSN:1094-687X, 1557-170X, 2375-7477
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Cross-sectional conductivity images of lower extremities were reconstructed using Magnetic Resonance Electrical Impedance Tomography (MREIT) techniques. Carbon-hydrogel electrodes were adopted for postmortem swine and in vivo human imaging experiments. Due to their large surface areas and good contacts on the skin, we could inject as much as 10 mA into the lower extremities of human subjects without producing a painful sensation. Using a 3T MREIT system, we first performed a series of postmortem swine experiments and produced high-resolution conductivity images of swine legs. Validating the experimental protocol for the lower extremities, we revised it for the following human experiments. After the review of the Institutional Review Board (IRB), we conducted our first MREIT experiments of human subjects using the same 3T MREIT system. Collecting magnetic flux density data inside lower extremities subject to multiple injection currents, we reconstructed cross-sectional conductivity images using the harmonic B z algorithm. The conductivity images very well distinguished different parts of muscles inside the lower extremities. The outermost fatty layer was clearly shown in each conductivity image. We could observe severe noise in the outer layer of the bones primarily due to the MR signal void phenomenon there. Reconstructed conductivity images indicated that the internal regions of the bones have relatively high conductivity values. Future study is desired in terms of the conductivity image reconstruction algorithm to improve the image quality. Further human imaging experiments are planned and being conducted to produce high-resolution conductivity images from different parts of the human body.
Bibliografie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISBN:9781424418145
1424418143
ISSN:1094-687X
1557-170X
2375-7477
DOI:10.1109/IEMBS.2008.4650540