Using claims data to predict dependency in activities of daily living as a proxy for frailty
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| Published in: | Pharmacoepidemiology and drug safety Vol. 24; no. 1; pp. 59 - 66 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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Blackwell Publishing Ltd
01.01.2015
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| ISSN: | 1053-8569, 1099-1557 |
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| Author | Jonsson Funk, Michele Faurot, Keturah R. Castillo, Wendy Camelo Brookhart, M. Alan Hanson, Laura C. Pate, Virginia Stürmer, Til Patrick, Amanda |
|---|---|
| AuthorAffiliation | 2 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill 4 Division of Geriatric Medicine, School of Medicine, University of North Carolina at Chapel Hill 5 Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland 1 Department of Physical Medicine and Rehabilitation, School of Medicine, University of North Carolina at Chapel Hill 3 Division of Pharmacoepidemiology, Brigham and Women’s Hospital |
| AuthorAffiliation_xml | – name: 1 Department of Physical Medicine and Rehabilitation, School of Medicine, University of North Carolina at Chapel Hill – name: 3 Division of Pharmacoepidemiology, Brigham and Women’s Hospital – name: 2 Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill – name: 4 Division of Geriatric Medicine, School of Medicine, University of North Carolina at Chapel Hill – name: 5 Pharmaceutical Health Services Research, School of Pharmacy, University of Maryland |
| Author_xml | – sequence: 1 givenname: Keturah R. surname: Faurot fullname: Faurot, Keturah R. email: faurot@med.unc.edu organization: Department of Physical Medicine and Rehabilitation, School of Medicine, University of North Carolina, Chapel Hill, NC, USA – sequence: 2 givenname: Michele surname: Jonsson Funk fullname: Jonsson Funk, Michele organization: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, NC, Chapel Hill, USA – sequence: 3 givenname: Virginia surname: Pate fullname: Pate, Virginia organization: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, NC, Chapel Hill, USA – sequence: 4 givenname: M. Alan surname: Brookhart fullname: Brookhart, M. Alan organization: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, NC, Chapel Hill, USA – sequence: 5 givenname: Amanda surname: Patrick fullname: Patrick, Amanda organization: Division of Pharmacoepidemiology, Brigham and Women's Hospital, MA, Boston, USA – sequence: 6 givenname: Laura C. surname: Hanson fullname: Hanson, Laura C. organization: Division of Geriatric Medicine, School of Medicine, University of North Carolina, NC, Chapel Hill, USA – sequence: 7 givenname: Wendy Camelo surname: Castillo fullname: Castillo, Wendy Camelo organization: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA – sequence: 8 givenname: Til surname: Stürmer fullname: Stürmer, Til organization: Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, NC, Chapel Hill, USA |
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| Notes | Supporting info item Versions of this work were presented at the International Conference on Pharmacoepidemiology & Therapeutic Risk Management in 2012 and 2013. Related work was also presented at the 2012 Scientific Meeting of the Gerontological Society of America. ArticleID:PDS3719 istex:B166671E5002C4AB4D444009B26E4308A141E4DE ark:/67375/WNG-NX422V47-V |
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| PublicationDate | 2015-01-01 |
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| PublicationDecade | 2010 |
| PublicationTitle | Pharmacoepidemiology and drug safety |
| PublicationTitleAlternate | Pharmacoepidemiol Drug Saf |
| PublicationYear | 2015 |
| Publisher | Blackwell Publishing Ltd |
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| References | Fried LP, Ferrucci L, Darer J, et al. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004; 59(3): 255-63. Groenwold RH, Hoes AW, Hak E. Impact of influenza vaccination on mortality risk among the elderly. Eur Respir J 2009; 34(1): 56-62. doi:10.1183/09031936.00190008. Kim DH and Schneeweiss S. Measuring frailty using claims data for pharmacoepidemiologic studies of mortality in older adults: evidence and recommendations. Pharmacoepidemiol Drug Saf 2014 Jun 24; DOI: 10.1002/pds.3674. Ensrud KE, Ewing SK, Taylor BC, et al. Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med 2008; 168(4): 382-9. doi:10.1001/archinternmed.2007.113. Boyd CM, Xue QL, Simpson CF, et al. Frailty, hospitalization, and progression of disability in a cohort of disabled older women. Am J Med 2005; 118(11): 1225-31. doi:10.1016/j.amjmed.2005.01.062. Katz S, Downs TD, Cash HR, et al. Progress in development of the index of ADL. Gerontologist 1970; 10(1): 20-30. Glynn RJ, Schneeweiss S, Wang PS, et al. Selective prescribing led to overestimation of the benefits of lipid-lowering drugs. J Clin Epidemiol 2006; 59(8): 819-28. doi:10.1016/j.jclinepi.2005.12.012. Searle SD, Mitnitski A, Gahbauer EA, et al. A standard procedure for creating a frailty index. BMC Geriatr 2008; 8: 24. doi:10.1186/1471-2318-8-24. Davidoff AJ, Zuckerman IH, Pandya N, et al. A novel approach to improve health status measurement in observational claims-based studies of cancer treatment and outcomes. Journal of geriatric oncology 2013; 4(2): 157-65. doi:10.1016/j.jgo.2012.12.005. Rockwood K, Hogan DB, MacKnight C. Conceptualisation and measurement of frailty in elderly people. Drugs Aging 2000; 17(4): 295-302. Keeler E, Guralnik JM, Tian H, et al. The impact of functional status on life expectancy in older persons. J Gerontol A Biol Sci Med Sci 2010; 65(7): 727-33. doi:10.1093/gerona/glq029. Groenwold RH, Hak E, Klungel OH, et al. Instrumental variables in influenza vaccination studies: mission impossible?!. Value Health 2010; 13(1): 132-7. doi:10.1111/j.1524-4733.2009.00584.x. Groenwold RH, Nelson DB, Nichol KL, et al. Sensitivity analyses to estimate the potential impact of unmeasured confounding in causal research. Int J Epidemiol 2010; 39(1): 107-17. doi:10.1093/ije/dyp332. Setoguchi S, Glynn RJ, Avorn J, et al. Statins and the risk of lung, breast, and colorectal cancer in the elderly. Circulation 2007; 115(1): 27-33. doi:10.1161/CIRCULATIONAHA.106.650176. Ray WA, Daugherty JR, Griffin MR. Lipid-lowering agents and the risk of hip fracture in a Medicaid population. Inj Prev 2002; 8(4): 276-9. Nichol KL, Nordin JD, Nelson DB, et al. Effectiveness of influenza vaccine in the community-dwelling elderly. N Engl J Med 2007; 357(14): 1373-81. doi:10.1056/NEJMoa070844. Stürmer T, Jonsson Funk M, Poole C, et al. Nonexperimental comparative effectiveness research using linked healthcare databases. Epidemiology 2011; 22(3): 298-301. doi:10.1097/EDE.0b013e318212640c. Walter LC, Brand RJ, Counsell SR, et al. Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization. JAMA 2001; 285(23): 2987-94. Noyes K, Liu H, Holloway R, et al. Accuracy of Medicare claims data in identifying Parkinsonism cases: comparison with the Medicare current beneficiary survey. Movement disorders : official journal of the Movement Disorder Society 2007; 22(4): 509-14. doi:10.1002/mds.21299. Stürmer T, Rothman KJ, Avorn J, et al. Treatment effects in the presence of unmeasured confounding: dealing with observations in the tails of the propensity score distribution--a simulation study. Am J Epidemiol 2010; 172(7): 843-54. doi:10.1093/aje/kwq198. Woods NF, LaCroix AZ, Gray SL, et al. Frailty: emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc 2005; 53(8): 1321-30. doi:10.1111/j.1532-5415.2005.53405.x. Jackson ML, Yu O, Nelson JC, et al. Further evidence for bias in observational studies of influenza vaccine effectiveness: the 2009 influenza A(H1N1) pandemic. Am J Epidemiol 2013; 178(8): 1327-36. doi:10.1093/aje/kwt124. Avila-Funes JA, Amieva H, Barberger-Gateau P, et al. Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study. J Am Geriatr Soc 2009; 57(3): 453-61. doi:10.1111/j.1532-5415.2008.02136.x. Jackson LA, Nelson JC, Benson P, et al. Functional status is a confounder of influenza vaccine and risk of all cause mortality in seniors. Int J Epidemiol 2006; 35(2): 345-352. doi:10.1093/ije/dyi274. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56(3): M146-56. Dormuth CR, Patrick AR, Shrank WH, et al. Statin adherence and risk of accidents: a cautionary tale. Circulation 2009; 119(15): 2051-7. doi:10.1161/CIRCULATIONAHA.108.824151. |
| References_xml | – reference: Groenwold RH, Hoes AW, Hak E. Impact of influenza vaccination on mortality risk among the elderly. Eur Respir J 2009; 34(1): 56-62. doi:10.1183/09031936.00190008. – reference: Groenwold RH, Hak E, Klungel OH, et al. Instrumental variables in influenza vaccination studies: mission impossible?!. Value Health 2010; 13(1): 132-7. doi:10.1111/j.1524-4733.2009.00584.x. – reference: Stürmer T, Rothman KJ, Avorn J, et al. Treatment effects in the presence of unmeasured confounding: dealing with observations in the tails of the propensity score distribution--a simulation study. Am J Epidemiol 2010; 172(7): 843-54. doi:10.1093/aje/kwq198. – reference: Woods NF, LaCroix AZ, Gray SL, et al. Frailty: emergence and consequences in women aged 65 and older in the Women's Health Initiative Observational Study. J Am Geriatr Soc 2005; 53(8): 1321-30. doi:10.1111/j.1532-5415.2005.53405.x. – reference: Fried LP, Ferrucci L, Darer J, et al. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci 2004; 59(3): 255-63. – reference: Kim DH and Schneeweiss S. Measuring frailty using claims data for pharmacoepidemiologic studies of mortality in older adults: evidence and recommendations. Pharmacoepidemiol Drug Saf 2014 Jun 24; DOI: 10.1002/pds.3674. – reference: Glynn RJ, Schneeweiss S, Wang PS, et al. Selective prescribing led to overestimation of the benefits of lipid-lowering drugs. J Clin Epidemiol 2006; 59(8): 819-28. doi:10.1016/j.jclinepi.2005.12.012. – reference: Katz S, Downs TD, Cash HR, et al. Progress in development of the index of ADL. Gerontologist 1970; 10(1): 20-30. – reference: Groenwold RH, Nelson DB, Nichol KL, et al. Sensitivity analyses to estimate the potential impact of unmeasured confounding in causal research. Int J Epidemiol 2010; 39(1): 107-17. doi:10.1093/ije/dyp332. – reference: Keeler E, Guralnik JM, Tian H, et al. The impact of functional status on life expectancy in older persons. J Gerontol A Biol Sci Med Sci 2010; 65(7): 727-33. doi:10.1093/gerona/glq029. – reference: Davidoff AJ, Zuckerman IH, Pandya N, et al. A novel approach to improve health status measurement in observational claims-based studies of cancer treatment and outcomes. Journal of geriatric oncology 2013; 4(2): 157-65. doi:10.1016/j.jgo.2012.12.005. – reference: Stürmer T, Jonsson Funk M, Poole C, et al. Nonexperimental comparative effectiveness research using linked healthcare databases. Epidemiology 2011; 22(3): 298-301. doi:10.1097/EDE.0b013e318212640c. – reference: Avila-Funes JA, Amieva H, Barberger-Gateau P, et al. Cognitive impairment improves the predictive validity of the phenotype of frailty for adverse health outcomes: the three-city study. J Am Geriatr Soc 2009; 57(3): 453-61. doi:10.1111/j.1532-5415.2008.02136.x. – reference: Setoguchi S, Glynn RJ, Avorn J, et al. Statins and the risk of lung, breast, and colorectal cancer in the elderly. Circulation 2007; 115(1): 27-33. doi:10.1161/CIRCULATIONAHA.106.650176. – reference: Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001; 56(3): M146-56. – reference: Ray WA, Daugherty JR, Griffin MR. Lipid-lowering agents and the risk of hip fracture in a Medicaid population. Inj Prev 2002; 8(4): 276-9. – reference: Dormuth CR, Patrick AR, Shrank WH, et al. Statin adherence and risk of accidents: a cautionary tale. Circulation 2009; 119(15): 2051-7. doi:10.1161/CIRCULATIONAHA.108.824151. – reference: Boyd CM, Xue QL, Simpson CF, et al. Frailty, hospitalization, and progression of disability in a cohort of disabled older women. Am J Med 2005; 118(11): 1225-31. doi:10.1016/j.amjmed.2005.01.062. – reference: Searle SD, Mitnitski A, Gahbauer EA, et al. A standard procedure for creating a frailty index. BMC Geriatr 2008; 8: 24. doi:10.1186/1471-2318-8-24. – reference: Nichol KL, Nordin JD, Nelson DB, et al. Effectiveness of influenza vaccine in the community-dwelling elderly. N Engl J Med 2007; 357(14): 1373-81. doi:10.1056/NEJMoa070844. – reference: Ensrud KE, Ewing SK, Taylor BC, et al. Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med 2008; 168(4): 382-9. doi:10.1001/archinternmed.2007.113. – reference: Rockwood K, Hogan DB, MacKnight C. Conceptualisation and measurement of frailty in elderly people. Drugs Aging 2000; 17(4): 295-302. – reference: Jackson LA, Nelson JC, Benson P, et al. Functional status is a confounder of influenza vaccine and risk of all cause mortality in seniors. Int J Epidemiol 2006; 35(2): 345-352. doi:10.1093/ije/dyi274. – reference: Walter LC, Brand RJ, Counsell SR, et al. Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization. JAMA 2001; 285(23): 2987-94. – reference: Noyes K, Liu H, Holloway R, et al. Accuracy of Medicare claims data in identifying Parkinsonism cases: comparison with the Medicare current beneficiary survey. Movement disorders : official journal of the Movement Disorder Society 2007; 22(4): 509-14. doi:10.1002/mds.21299. – reference: Jackson ML, Yu O, Nelson JC, et al. Further evidence for bias in observational studies of influenza vaccine effectiveness: the 2009 influenza A(H1N1) pandemic. Am J Epidemiol 2013; 178(8): 1327-36. doi:10.1093/aje/kwt124. |
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| Title | Using claims data to predict dependency in activities of daily living as a proxy for frailty |
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