Vitamin D receptor is not required for the rapid actions of 1,25-dihydroxyvitamin D3 to increase intracellular calcium and activate protein kinase C in mouse osteoblasts

The rapid, non‐genomic actions of 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3] have been well described, however, the role of the nuclear vitamin D receptor (VDR) in this pathway remains unclear. To address this question, we used VDR(+/+) and VDR(−/−) osteoblasts isolated from wild‐type and VDR null mice...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Journal of cellular biochemistry Ročník 88; číslo 4; s. 794 - 801
Hlavní autoři:	Wali, Ramesh K., Kong, Juan, Sitrin, Michael D., Bissonnette, Marc, Li, Yan Chun
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New York Wiley Subscription Services, Inc., A Wiley Company 01.03.2003
Témata:	Animals Calcitriol - pharmacology Calcitriol - physiology calcium Calcium - analysis Calcium - metabolism Cells, Cultured Dose-Response Relationship, Drug Enzyme Activation - drug effects Enzyme Inhibitors - pharmacology Indoles - pharmacology Isoenzymes - biosynthesis Maleimides - pharmacology Mice Mice, Knockout non-genomic actions Osteoblasts - drug effects Osteoblasts - physiology Phosphorylation - drug effects protein kinase C Protein Kinase C - analysis Protein Kinase C - antagonists & inhibitors Protein Kinase C - biosynthesis Protein Kinase C - metabolism Receptors, Calcitriol - genetics Receptors, Calcitriol - physiology RNA - analysis RNA - isolation & purification VDR vitamin D
ISSN:	0730-2312, 1097-4644
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!