Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events

Entry and progression through mitosis has traditionally been linked directly to the activity of cyclin-dependent kinase 1 (Cdk1). In this study we utilized low doses of the Cdk1-specific inhibitor, RO3306 from early G 2 phase onwards. Addition of low doses of RO3306 in G 2 phase induced minor chromo...

Celý popis

Podrobná bibliografia

Vydané v:	Cell cycle (Georgetown, Tex.) Ročník 13; číslo 9; s. 1400 - 1412
Hlavní autori:	McCloy, Rachael A, Rogers, Samuel, Caldon, C Elizabeth, Lorca, Thierry, Castro, Anna, Burgess, Andrew
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Taylor & Francis 01.05.2014 Landes Bioscience
Predmet:	Cdk1 cyclin B1 mitosis PP2A RO3306 SAC
ISSN:	1538-4101, 1551-4005
On-line prístup:	Získať plný text
Tagy:	Pridať tag Žiadne tagy, Buďte prvý, kto otaguje tento záznam!