A Block Recursive Algorithm for Sequence Alignment

Based on a new way to compute check points, this paper presents a "Block Recursive" sequence alignment algorithm, which can run in a time requirement between 1.5 mn and 3 mn in general cases but between 1.5 mn and 2 mn for sequences with high similarities. Still, the algorithm keeps a line...

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Veröffentlicht in:2008 2nd International Conference on Bioinformatics and Biomedical Engineering Jg. 2; S. 604 - 607
Hauptverfasser: Wang, Fang-Yuan, Li, Yu-Jian
Format: Tagungsbericht Journal Article
Sprache:Englisch
Veröffentlicht: IEEE 2008
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ISBN:9781424417476, 1424417473
ISSN:2151-7614
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Zusammenfassung:Based on a new way to compute check points, this paper presents a "Block Recursive" sequence alignment algorithm, which can run in a time requirement between 1.5 mn and 3 mn in general cases but between 1.5 mn and 2 mn for sequences with high similarities. Still, the algorithm keeps a linear space requirement and always guarantees an optimal alignment result. Some experiments show that it runs at least 10% faster than the Hirschberg algorithm if the two compared sequences has a normalized edit distance less than 0.25.
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ISBN:9781424417476
1424417473
ISSN:2151-7614
DOI:10.1109/ICBBE.2008.147