Roadmap for Causal Inference in Safety Analysis

Jordan C. Brooks, Alan S. Go, Daniel E. Singer, and Mark J. van der LaanSafety analysis involves assessing the causal effect of a treatment or exposure regimen on one or more outcomes of interest based on observing a sample of subjects over time. The observed data might constitute an observational s...

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Vydané v:	Quantitative Evaluation of Safety in Drug Development s. 190 - 211
Médium:	Kapitola
Jazyk:	English
Vydavateľské údaje:	United Kingdom Chapman and Hall/CRC 2015 CRC Press LLC
Predmet:	Clinical trials Pharmaceutical technology Probability & statistics Causal Quantities True Q0 Self-controlled Case Series Van Der Laan Condence Intervals Target Parameter Structural Causal Model Clever Covariate Safety Analysis Multiple Testing Procedure Intervention Nodes HLGT Exclusion Restriction Assumption DMC Member Data Monitoring Committee Linear Discriminant Analysis Observed Data Structure Efcient Estimators Standardize MedDRA Query Asymptotic Linearity Time Dependent Covariates Non-inferiority Trials Cox Proportional Hazards Regression Model Super Learner
ISBN:	9781466555457, 1466555459
On-line prístup:	Získať plný text
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