Ca2+ channel subtypes and pharmacology in the kidney

A large body of evidence has accrued indicating that voltage-gated Ca(2+) channel subtypes, including L-, T-, N-, and P/Q-type, are present within renal vascular and tubular tissues, and the blockade of these Ca(2+) channels produces diverse actions on renal microcirculation. Because nifedipine acts...

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Bibliographic Details
Published in:	Circulation research Vol. 100; no. 3; p. 342
Main Authors:	Hayashi, Koichi, Wakino, Shu, Sugano, Naoki, Ozawa, Yuri, Homma, Koichiro, Saruta, Takao
Format:	Journal Article
Language:	English
Published:	United States 16.02.2007
Subjects:	Aldosterone - physiology Animals Antihypertensive Agents - adverse effects Antihypertensive Agents - classification Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Arterioles - drug effects Arterioles - physiology Blood Pressure - drug effects Calcium Channel Blockers - adverse effects Calcium Channel Blockers - pharmacology Calcium Channel Blockers - therapeutic use Calcium Channels - chemistry Calcium Channels - classification Calcium Channels - drug effects Calcium Channels - physiology Calcium Channels, L-Type - chemistry Calcium Channels, L-Type - drug effects Calcium Channels, L-Type - physiology Calcium Channels, N-Type - chemistry Calcium Channels, N-Type - drug effects Calcium Channels, N-Type - physiology Calcium Channels, T-Type - chemistry Calcium Channels, T-Type - drug effects Calcium Channels, T-Type - physiology Calcium Signaling - drug effects Calcium Signaling - physiology Cardiovascular Diseases - drug therapy Cardiovascular Diseases - physiopathology Diabetes Mellitus - physiopathology Disease Progression Humans Hydronephrosis - physiopathology Hypertension - drug therapy Hypertension - physiopathology Kidney - blood supply Kidney - drug effects Kidney - physiology Kidney Diseases - drug therapy Kidney Diseases - metabolism Mice Mice, Knockout Microcirculation - drug effects Microcirculation - physiology Models, Biological Neurotransmitter Agents - secretion Protein Subunits Rats Renal Circulation - drug effects Renal Circulation - physiology Renin - secretion Renin-Angiotensin System - physiology Vasodilation - drug effects
ISSN:	1524-4571, 1524-4571
Online Access:	Get more information
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