Prediction of response to neoadjuvant chemoendocrine therapy in primary breast carcinomas

Our aim was to determine whether biological molecular markers can predict response to neoadjuvant chemoendocrine therapy in patients with early breast cancer. Ninety patients (median age 56 years; range, 28-69 years) with primary operable breast carcinoma were studied. They were treated with four 3-...

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Vydané v:	Clinical cancer research Ročník 3; číslo 4; s. 593
Hlavní autori:	Makris, A, Powles, T J, Dowsett, M, Osborne, C K, Trott, P A, Fernando, I N, Ashley, S E, Ormerod, M G, Titley, J C, Gregory, R K, Allred, D C
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.04.1997
Predmet:	Adult Age Factors Aged Antineoplastic Agents, Hormonal - administration & dosage Antineoplastic Agents, Hormonal - therapeutic use Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biopsy, Needle Breast Neoplasms - drug therapy Breast Neoplasms - pathology Breast Neoplasms - radiotherapy Breast Neoplasms - surgery Chemotherapy, Adjuvant Combined Modality Therapy Disease Progression Female Humans Menopause Middle Aged Mitomycin - administration & dosage Mitoxantrone - administration & dosage Neoplasm Staging Ploidies Predictive Value of Tests Proto-Oncogene Proteins c-bcl-2 - analysis Receptors, Estrogen - analysis Receptors, Progesterone - analysis S Phase Tamoxifen - administration & dosage Tamoxifen - therapeutic use
ISSN:	1078-0432
On-line prístup:	Zistit podrobnosti o prístupe
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