Exclusion of Polymorphisms in Carnosinase Genes (CNDP1 and CNDP2) as a Cause of Diabetic Nephropathy in Type 1 Diabetes : Results of Large Case-Control and Follow-Up Studies

Recently, an association was found between diabetic nephropathy and the D18S880 microsatellite, located in the carnosinase gene (CNDP1) on chromosome 18q. Alleles of this microsatellite encode for a variable number of leucine residues (from four to seven) in the leader peptide of the carnosinase pre...

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Bibliographic Details
Published in:	Diabetes (New York, N.Y.) Vol. 57; no. 9; pp. 2547 - 2551
Main Authors:	WANIC, Krzysztof, PLACHA, Grzegorz, DUNN, Jonathon, SMILES, Adam, WARRAM, James H, KROLEWSKI, Andrzej S
Format:	Journal Article
Language:	English
Published:	Alexandria, VA American Diabetes Association 01.09.2008
Subjects:	Adult Associated diseases and complications Biological and medical sciences Case-Control Studies Control Creatinine Diabetes Diabetes Mellitus, Type 1 - epidemiology Diabetes Mellitus, Type 1 - genetics Diabetes. Impaired glucose tolerance Diabetic nephropathies Diabetic Nephropathies - epidemiology Diabetic Nephropathies - genetics Diabetic nephropathy Diabetics Dipeptidases - genetics Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Female Follow-Up Studies Genes Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease - epidemiology Genetics Genotype Health aspects Humans Incidence Kidney diseases Kidneys Male Medical examination Medical sciences Microsatellite Repeats Middle Aged Nephrology. Urinary tract diseases Peptides Physiological aspects Polymorphism, Single Nucleotide Research design Risk Factors Urinary system involvement in other diseases. Miscellaneous White people Poland Endocrinopathy Kidney disease Immunopathology Concomitant disease Urinary system disease Gene Type 1 diabetes Follow up study Autoimmune disease Diabetic nephropathy Polymorphism
ISSN:	0012-1797, 1939-327X, 1939-327X
Online Access:	Get full text
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