The biogenesis, biology and characterization of circular RNAs

Circular RNAs (circRNAs) are covalently closed, endogenous biomolecules in eukaryotes with tissue-specific and cell-specific expression patterns, whose biogenesis is regulated by specific cis-acting elements and trans-acting factors. Some circRNAs are abundant and evolutionarily conserved, and many...

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Vydáno v:	Nature reviews. Genetics Ročník 20; číslo 11; s. 675 - 691
Hlavní autoři:	Kristensen, Lasse S, Andersen, Maria S, Stagsted, Lotte V W, Ebbesen, Karoline K, Hansen, Thomas B, Kjems, Jørgen
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Nature Publishing Group 01.11.2019
Témata:	Biosynthesis Cardiovascular diseases Cardiovascular Diseases - genetics Cardiovascular Diseases - metabolism Computational neuroscience Diabetes mellitus Diabetes Mellitus - genetics Diabetes Mellitus - metabolism Humans MicroRNAs - biosynthesis MicroRNAs - genetics miRNA Neoplasms - genetics Neoplasms - metabolism Nervous System Diseases - genetics Nervous System Diseases - metabolism Neurological diseases RNA, Circular - biosynthesis RNA, Circular - genetics RNA, Neoplasm - biosynthesis RNA, Neoplasm - genetics
ISSN:	1471-0056, 1471-0064, 1471-0064
On-line přístup:	Získat plný text
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