Construction of a eukaryotic expression plasmid for human retina-derived neurotrophin-3

Neurotrophin-3 (NT-3) can promote the repair of central nervous system and retinal damage. In previous reports, NT-3 has been expressed by viral vectors. However, plasmid vectors have a safer profile compared with viral vectors in clinical studies. This study recombined amplified human retinal NT-3...

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Veröffentlicht in:	Neural regeneration research Jg. 8; H. 11; S. 1031 - 1040
Hauptverfasser:	Peng, Chunxia, Yin, Xiaobei, Li, Mengda, He, Ting, Li, Genlin
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	India Medknow Publications and Media Pvt. Ltd 15.04.2013 Beijing Tongren Eye Center,Beijing Tongren Hospital, Capital Medical University, Beijing Key Laboratory of Ophthalmology & Visual Sciences, Beijing 100730, China Medknow Publications & Media Pvt Ltd
Schlagworte:	Bioengineering Methods Neurodegenerative Disease and Neural Regeneration Neurotrophic functions Physiological aspects Plasmids Retina encapsulated cell technology fusion protein neural regeneration neuroregeneration grants-supported paper plasmid retinitis pigmentosa gene therapy biological factor neurotrophin-3
ISSN:	1673-5374, 1876-7958
Online-Zugang:	Volltext
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