Biomarkers of epithelial-mesenchymal transition: E-cadherin and beta-catenin in malignant transformation of oral lesions

Detecting oral lesions at high risk of becoming cancer may enable early interventions to prevent oral cancer. The diagnosis of dysplasia in an oral lesion is used to predict this risk but is subject to interobserver and intraobserver variability. Studying biomarkers or molecular markers that reflect...

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Bibliographic Details
Published in:	Canadian Journal of Dental Hygiene Vol. 58; no. 2; pp. 111 - 119
Main Authors:	Yim, Ilena S, Laronde, Denise M
Format:	Journal Article Trade Publication Article
Language:	English
Published:	Canada The Canadian Dental Hygienists Association 01.06.2024 Canadian Dental Hygienists Association CJDH
Subjects:	Basement membranes beta Catenin - genetics beta Catenin - metabolism Biological markers Biomarkers Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Cadherins Cadherins - genetics Cadherins - metabolism Cancer Cell junctions Cell Transformation, Neoplastic - genetics Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Development and progression Diagnosis Dysplasia E-cadherin Epithelial cells Epithelial-Mesenchymal Transition Epithelium Extracellular matrix Head & neck cancer Health aspects Humans Keratin Lesions Literature Review Mesenchyme Morbidity Motility Mouth Neoplasms - diagnosis Mouth Neoplasms - metabolism Mouth Neoplasms - pathology Oncology, Experimental Oral cancer Oral cavity Patients Pharynx Prevention Risk assessment Roles Squamous cell carcinoma Stem cells Wnt Signaling Pathway β-Catenin Canada epithelial–mesenchymal transition beta catenin mouth malignant transformation oral epithelial dysplasia risk cadherins neoplasms
ISSN:	1712-171X, 1712-1728
Online Access:	Get full text
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