Fat .sub.max as an index of aerobic exercise performance in mice during uphill running
Endurance exercise performance has been used as a representative index in experimental animal models in the field of health sciences, exercise physiology, comparative physiology, food function or nutritional physiology. The objective of the present study was to evaluate the effectiveness of Fat.sub....
Uloženo v:
| Vydáno v: | PloS one Ročník 13; číslo 2; s. e0193470 |
|---|---|
| Hlavní autoři: | , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
| Vydáno: |
Public Library of Science
23.02.2018
|
| Témata: | |
| ISSN: | 1932-6203, 1932-6203 |
| On-line přístup: | Získat plný text |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
|
| Abstract | Endurance exercise performance has been used as a representative index in experimental animal models in the field of health sciences, exercise physiology, comparative physiology, food function or nutritional physiology. The objective of the present study was to evaluate the effectiveness of Fat.sub.max (the exercise intensity that elicits maximal fat oxidation) as an additional index of endurance exercise performance that can be measured during running at submaximal exercise intensity in mice. We measured both Fat.sub.max and Vo.sub.2 peak of trained ICR mice that voluntary exercised for 8 weeks and compared them with a sedentary group of mice at multiple inclinations of 20, 30, 40, and 50° on a treadmill. The Vo.sub.2 at Fat.sub.max of the training group was significantly higher than that of the sedentary group at inclinations of 30 and 40° (P < 0.001). The running speed at Fat.sub.max of the training group was significantly higher than that of the sedentary group at inclinations of 20, 30, and 40° (P < 0.05). Blood lactate levels sharply increased in the sedentary group (7.33 ± 2.58 mM) compared to the training group (3.13 ± 1.00 mM, P < 0.01) when running speeds exceeded the Fat.sub.max of sedentary mice. Vo.sub.2 at Fat.sub.max significantly correlated to Vo.sub.2 peak, running time to fatigue, and lactic acid level during running (P < 0.05) although the reproducibility of Vo.sub.2 peak was higher than that of Vo.sub.2 at Fat.sub.max . In conclusion, Fat.sub.max can be used as a functional assessment of the endurance exercise performance of mice during submaximal exercise intensity. |
|---|---|
| AbstractList | Endurance exercise performance has been used as a representative index in experimental animal models in the field of health sciences, exercise physiology, comparative physiology, food function or nutritional physiology. The objective of the present study was to evaluate the effectiveness of Fat.sub.max (the exercise intensity that elicits maximal fat oxidation) as an additional index of endurance exercise performance that can be measured during running at submaximal exercise intensity in mice. We measured both Fat.sub.max and Vo.sub.2 peak of trained ICR mice that voluntary exercised for 8 weeks and compared them with a sedentary group of mice at multiple inclinations of 20, 30, 40, and 50° on a treadmill. The Vo.sub.2 at Fat.sub.max of the training group was significantly higher than that of the sedentary group at inclinations of 30 and 40° (P < 0.001). The running speed at Fat.sub.max of the training group was significantly higher than that of the sedentary group at inclinations of 20, 30, and 40° (P < 0.05). Blood lactate levels sharply increased in the sedentary group (7.33 ± 2.58 mM) compared to the training group (3.13 ± 1.00 mM, P < 0.01) when running speeds exceeded the Fat.sub.max of sedentary mice. Vo.sub.2 at Fat.sub.max significantly correlated to Vo.sub.2 peak, running time to fatigue, and lactic acid level during running (P < 0.05) although the reproducibility of Vo.sub.2 peak was higher than that of Vo.sub.2 at Fat.sub.max . In conclusion, Fat.sub.max can be used as a functional assessment of the endurance exercise performance of mice during submaximal exercise intensity. |
| Audience | Academic |
| Author | Taniguchi, Hirokazu Ishihara, Kengo |
| Author_xml | – sequence: 1 fullname: Ishihara, Kengo – sequence: 2 fullname: Taniguchi, Hirokazu |
| BookMark | eNqNkMtqwzAQRUVJoUnaP-hCUCh0YVfyQ1aWITRtIBDoI9swkUeOgi0FywZ_fgXtIoEuyizmzuXMwJ0JGVlnkZB7zmKeFvz56PrWQh2fgh0zPkuzgl2RcRBJJBKWjs70DZl4f2QsT6UQY7JdQkdj3-_jBgYKnoKlxpY4UKcpYOv2RlEcsFXGIz1hq13bgFUYKNqY0Mu-Nbai_elg6pq2vbVhvCXXGmqPd799Sr6WL5-Lt2i9eV0t5uuo4kJkEWYFprkEZKVQWnJWCEApFSs4mzEJKkOGQkjJAUpdSJ0kmkFeMJVludxDOiUPP3crqHFnrHZdC6oxXu3meRISpnmeBSr-gwpVYogQnqZN8C8Wni4WAtPh0FXQe79bfbz_n91sL9nHM_aAUHcH7-q-M876c_AbE0uPOQ |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2018 Public Library of Science |
| Copyright_xml | – notice: COPYRIGHT 2018 Public Library of Science |
| DBID | IOV ISR |
| DOI | 10.1371/journal.pone.0193470 |
| DatabaseName | Gale In Context: Opposing Viewpoints Gale In Context: Science |
| DatabaseTitleList | |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Sciences (General) |
| EISSN | 1932-6203 |
| ExternalDocumentID | A528663554 |
| GeographicLocations | Japan |
| GeographicLocations_xml | – name: Japan |
| GroupedDBID | --- 123 29O 2WC 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ AAUCC AAWOE ABDBF ABIVO ABJCF ABUWG ACGFO ACIHN ACIWK ACPRK ACUHS ADBBV ADRAZ AEAQA AENEX AEUYN AFKRA AFPKN AFRAH AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAWUL BBNVY BBORY BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CS3 D1I D1J D1K DIK DU5 E3Z EAP EAS EBD EMOBN ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IGS IHR IHW INH INR IOV IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ O5R O5S OK1 P2P P62 PATMY PDBOC PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO PTHSS PV9 PYCSY RNS RPM RZL SV3 TR2 UKHRP WOQ WOW ~02 ~KM ACCTH AFFHD BAIFH BBTPI OVT PJZUB PPXIY PQGLB |
| ID | FETCH-LOGICAL-g1664-e47e358ae0d6cf81076ae88c0710908ac4e0e66881aadf78f22f0a570c4458ba3 |
| ISSN | 1932-6203 |
| IngestDate | Sat Nov 29 13:09:52 EST 2025 Sat Nov 29 10:17:15 EST 2025 Wed Nov 26 10:39:19 EST 2025 Wed Nov 26 10:40:02 EST 2025 Thu May 22 21:16:05 EDT 2025 |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 2 |
| Language | English |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-g1664-e47e358ae0d6cf81076ae88c0710908ac4e0e66881aadf78f22f0a570c4458ba3 |
| PageCount | e0193470 |
| ParticipantIDs | gale_infotracmisc_A528663554 gale_infotracacademiconefile_A528663554 gale_incontextgauss_ISR_A528663554 gale_incontextgauss_IOV_A528663554 gale_healthsolutions_A528663554 |
| PublicationCentury | 2000 |
| PublicationDate | 20180223 |
| PublicationDateYYYYMMDD | 2018-02-23 |
| PublicationDate_xml | – month: 02 year: 2018 text: 20180223 day: 23 |
| PublicationDecade | 2010 |
| PublicationTitle | PloS one |
| PublicationYear | 2018 |
| Publisher | Public Library of Science |
| Publisher_xml | – name: Public Library of Science |
| SSID | ssj0053866 |
| Score | 2.2450826 |
| Snippet | Endurance exercise performance has been used as a representative index in experimental animal models in the field of health sciences, exercise physiology,... |
| SourceID | gale |
| SourceType | Aggregation Database |
| StartPage | e0193470 |
| SubjectTerms | Aerobic exercises Physical fitness Physiological aspects |
| Title | Fat .sub.max as an index of aerobic exercise performance in mice during uphill running |
| Volume | 13 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: DOA dateStart: 20060101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M~E dateStart: 20060101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Advanced Technologies & Aerospace Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: P5Z dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/hightechjournals providerName: ProQuest – providerCode: PRVPQU databaseName: Agriculture Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M0K dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/agriculturejournals providerName: ProQuest – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M7P dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Engineering Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M7S dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com providerName: ProQuest – providerCode: PRVPQU databaseName: Environmental Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: PATMY dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/environmentalscience providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 7X7 dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: Materials Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: KB. dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/materialsscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Nursing & allied health premium. customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 7RV dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: BENPR dateStart: 20061201 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Public Health Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 8C1 dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/publichealth providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: PIMPY dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVATS databaseName: Public Library of Science (PLoS) Journals Open Access customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: FPL dateStart: 20060101 isFulltext: true titleUrlDefault: http://www.plos.org/publications/ providerName: Public Library of Science |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9QwELagcOBSUR6ipRQLIQFapXVsJ3aOFaKil1Kxpept5TjOEgHJKtmgFb-eseNks9DDcuASRd7ZPPw54_Hjmw-h1ynT0AtkNOBSZQFPeRakKWeB4FmYMUEimREnNiEuLuTNTXLpKQSNkxMQZSlXq2TxX6GGMgDbUmf_Ae7holAA5wA6HAF2OG4F_BkM-Z2y1Q-1sioyyu5lzMzKrfgbm3ZJD0JLNmvxwBsoyonVpu-Zi-3CLhRM6taJGo2D2Mvv1XRSrdfjz5uvhc377Hk-82o9HVAWc6u24jq4oq6-qV_teJ4hlI63zYaW0c0iTjybwjFqOuczcp4QCwYxJd2fzC1lvcdlo5ZFR-7TQMDJeKck8pdvZ8L59q6mjxfwmscj8z-yZp9GVHbB1F10j4ooSdy2zmnfS4Ofd-vYw_N5WiXc5OS2W_geexR7XD1Eu37QgE87sPfQHVM-Qnu-Zhr81ucOf_cYXQP6uEcfqwarEjv0cZVjjz7u0ccj9MEKW_Rxhz7u0Mce_Sfoy9mHq_cfAy-dEczDOOaB4cKwSCpDsljnEsb4sTJSahtQJkQqzQ0xcSxlqFSWC5lTmhMVCaI5j2Sq2FO0U8LrP0OY8VSkNk1kRBMOPWNCTErDnGhKDJyl--ilrZlZx9sdvqDZGoF99MpZ2HQjpd3PNFdt08zOP11vYTT9vGH0xhvl1bJWWnkOCTypTWO2YXm4YQlOU49-Ptj6Qs_Rg_XXcIh2lnVrXqD7-ueyaOojN4Vz5FrWb3oEjTM |
| linkProvider | ProQuest |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Fat+.sub.max+as+an+index+of+aerobic+exercise+performance+in+mice+during+uphill+running&rft.jtitle=PloS+one&rft.au=Ishihara%2C+Kengo&rft.au=Taniguchi%2C+Hirokazu&rft.date=2018-02-23&rft.pub=Public+Library+of+Science&rft.issn=1932-6203&rft.eissn=1932-6203&rft.volume=13&rft.issue=2&rft.spage=e0193470&rft_id=info:doi/10.1371%2Fjournal.pone.0193470&rft.externalDocID=A528663554 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon |