Mining Affymetrix microarray data for long non-coding RNAs: altered expression in the nucleus accumbens of heroin abusers

J. Neurochem. (2011) 116, 459-466. ABSTRACT: Although recent data suggest that some long non-coding RNAs (lncRNAs) exert widespread effects on gene expression and organelle formation, lncRNAs as a group constitute a sizable but poorly characterized fraction of the human transcriptome. We investigate...

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Vydáno v:	Journal of neurochemistry Ročník 116; číslo 3; s. 459 - 466
Hlavní autoři:	Michelhaugh, Sharon K, Lipovich, Leonard, Blythe, Jason, Jia, Hui, Kapatos, Gregory, Bannon, Michael J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Oxford, UK Blackwell Publishing Ltd 01.02.2011 Wiley-Blackwell
Témata:	Abundance Addictive behaviors Adult and adolescent clinical studies Analgesics, Opioid - adverse effects Biological and medical sciences Brain Brain Chemistry - drug effects Brain Chemistry - genetics Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Computational neuroscience Data Mining - methods Data processing DNA microarrays Drug abuse Drug addiction Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation - drug effects Gene Expression Regulation - genetics Genetic Markers - drug effects Genetic Markers - physiology Heroin Heroin - adverse effects Heroin Dependence - genetics Heroin Dependence - metabolism Humans lncRNA MALAT1 Medical sciences MEG3 MIAT NEAT1 non-coding RNA Nucleus accumbens Nucleus Accumbens - drug effects Nucleus Accumbens - metabolism Oligonucleotide Array Sequence Analysis - methods Organelles Polymerase chain reaction Polymerase Chain Reaction - methods Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Reward Ribonucleic acid RNA RNA, Untranslated - biosynthesis RNA, Untranslated - drug effects RNA, Untranslated - genetics Up-Regulation - drug effects Up-Regulation - genetics Vertebrates: nervous system and sense organs Human MEG3 Drug addiction Central nervous system IncRNA Basal ganglion Substance abuse MIAT Gene expression NEAT1 Encephalon Nucleus accumbens Coding MALAT1
ISSN:	0022-3042, 1471-4159, 1471-4159
On-line přístup:	Získat plný text
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