DNA Repair in Mammalian Cells

Arrest of transcription at sites of DNA damage represents a strong signal for apoptosis. To overcome the impasse represented by transcription complexes arrested at sites of damage, cells have evolved a specialized nucleotide excision repair (NER) pathway called transcription-coupled DNA repair (TCR)...

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Bibliographic Details

Published in:	Cellular and molecular life sciences : CMLS Vol. 66; no. 6; pp. 1010 - 1020
Main Author:	Tornaletti, S
Format:	Journal Article
Language:	English
Published:	Basel Basel : Birkhäuser-Verlag 01.03.2009 Springer Nature B.V
Subjects:	Apoptosis Damage Deoxyribonucleic acid DNA DNA damage DNA repair genome humans Lesions Mammalian cells Nucleotide excision repair Nucleotides Transcription transcription (genetics) Transcription elongation
ISSN:	1420-682X, 1420-9071
Online Access:	Get full text
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