Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes After Intensive Statin Treatment: The YELLOW II Study

Despite extensive evidence demonstrating the beneficial effects of statins on clinical outcomes, the mechanisms underlying these effects remain elusive. This study assessed changes in plaque morphology using intravascular imaging, with a comprehensive evaluation of cholesterol efflux capacity (CEC)...

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Bibliographic Details
Published in:	Journal of the American College of Cardiology Vol. 69; no. 6; pp. 628 - 640
Main Authors:	Kini, Annapoorna S, Vengrenyuk, Yuliya, Shameer, Khader, Maehara, Akiko, Purushothaman, Meerarani, Yoshimura, Takahiro, Matsumura, Mitsuaki, Aquino, Melissa, Haider, Nezam, Johnson, Kipp W, Readhead, Ben, Kidd, Brian A, Feig, Jonathan E, Krishnan, Prakash, Sweeny, Joseph, Milind, Mahajan, Moreno, Pedro, Mehran, Roxana, Kovacic, Jason C, Baber, Usman, Dudley, Joel T, Narula, Jagat, Sharma, Samin
Format:	Journal Article
Language:	English
Published:	United States 14.02.2017
Subjects:	Coronary Artery Disease - blood Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - therapy Delta-5 Fatty Acid Desaturase Female Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Leukocytes, Mononuclear Male Multimodal Imaging Percutaneous Coronary Intervention Plaque, Atherosclerotic - blood Plaque, Atherosclerotic - diagnostic imaging Plaque, Atherosclerotic - therapy Prospective Studies Rosuvastatin Calcium - therapeutic use Tomography, Optical Coherence Transcriptome high-dose statin optical coherence tomography thin-cap fibroatheroma fibrous cap thickness plaque stability
ISSN:	1558-3597
Online Access:	Get more information
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